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The effect of music intervention on sedation in elderly patients undergoing transurethral resection of prostate under spinal anesthesia: a prospective randomized controlled clinical trial

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Abstract

Purpose

Music intervention is commonly used as a non-pharmacologic therapeutic modality to alleviate anxiety in perioperative patients. This study aimed to assess the sedative and anxiolytic effects of music on elderly patients receiving transurethral resection of prostate (TURP) under spinal anesthesia.

Methods

This was a prospective randomized controlled trial on patients who aged over 60 and received TURP under spinal anesthesia. Participants were randomized to the music group or the control group (no music). The primary outcome was perioperative BIS values, and the secondary outcomes were patient’s perioperative anxiety levels, heart rate (HR), blood pressure, and patient satisfaction score.

Results

A total of 82 patients were analyzed. The perioperative BIS values in the music group were significantly lower than those of the control group at almost all time points (P < 0.001), as well as showed a significant reduction compared with baseline (P < 0.001), whereas the control group did not. In comparison with the control group, systolic blood pressure (SBP) significantly decreased in the music group at the beginning (mean difference, − 8.0 mmHg; 95% CI − 15.70 to 0.35; P = 0.041) and the 60th minute (mean difference, − 7.9 mmHg; 95% CI − 15.30 to 0.51; P = 0.037) of TURP. Furthermore, compared with baseline within the music group, diastolic blood pressure (DBP) and HR significant reduced at whole time points (P < 0.05), yet the control group not.

Conclusion

Music intervention effectively provided slight sedation for elderly patients when undergoing TURP under spinal anesthesia without sedatives.

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Data availability

Data of this study were available on the Clinical Trial Management Public Platform (http://www.medresman.org.cn).

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Acknowledgements

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Funding

This work was funded by Liaoning Natural Science Foundation of China [2020-MS-053].

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Authors and Affiliations

  1. Department of Anesthesiology, People’s Hospital of China Medical University (People’s Hospital of Liaoning Province), No. 33 Wenyi Road, Shenyang, 110016, China

    Yi-Wen Zhang, Ling-Ling Wang, Chang-Ming Wang & Jing Zhang

  2. Department of Anesthesiology, Jinqiu Hospital of Liaoning Province, No. 317 Xiaonan Street, Shenyang, 110016, China

    Zhan-Ying Guan

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  1. Yi-Wen Zhang
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  2. Zhan-Ying Guan
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  3. Ling-Ling Wang
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  4. Chang-Ming Wang
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  5. Jing Zhang
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All authors listed in this manuscript have contributed substantially with planning, conducting, reporting, designing, analyzing, interpreting the data and in writing and editing the manuscript.

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Correspondence to Zhan-Ying Guan or Chang-Ming Wang.

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Zhang, YW., Guan, ZY., Wang, LL. et al. The effect of music intervention on sedation in elderly patients undergoing transurethral resection of prostate under spinal anesthesia: a prospective randomized controlled clinical trial. J Anesth 37, 734–740 (2023). https://doi.org/10.1007/s00540-023-03225-0

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  • DOI: https://doi.org/10.1007/s00540-023-03225-0

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