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A systematic review of otologic injuries sustained in civilian terrorist explosions

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Abstract

Purpose

Determine the prevalence of otological symptoms and tympanic membrane perforation, healing rates of tympanic membrane perforation with surgical and conservative management, and hearing function in civilian victims of terrorist explosions.

Methods

A systematic review was conducted with searches on Medline, Embase, EMCare and CINAHL for publications between the 1st January 1945 and 26th May 2023. Studies with quantitative data addressing our aims were included. This review is registered with PROSPERO: CRD42020166768. Among 2611 studies screened, 18 studies comprising prospective and retrospective cohort studies were included.

Results

The percentage of eardrums perforated in patients admitted to hospital, under ENT follow up and attending the emergency department is 69.0% (CI 55.5–80.5%), 38.7% (CI 19.0–63.0%, I2 0.715%) and 21.0% (CI 11.9–34.3%, I2 0.718%) respectively. Perforated eardrums heal spontaneously in 62.9% (CI 50.4–73.8%, I2 0.687%) of cases and in 88.8% (CI 75.9–96.3%, I2 0.500%) of cases after surgery. Common symptoms present within one month of bombings are tinnitus 84.7% (CI 70.0–92.9%, I2 0.506%), hearing loss 83.0% (CI 64.5–92.9%, I2 0.505%) and ear fullness 59.7% (CI 13.4–93.4%, I2 0.719). Symptomatic status between one and six months commonly include no symptoms 57.5% (CI 46.0–68.3%), hearing loss 35.4% (CI 21.8–51.8%, I2 0.673%) and tinnitus 15.6% (CI 4.9–40.0%, I2 0.500%). Within one month of bombings, the most common hearing abnormality is sensorineural hearing loss affecting 26.9% (CI 16.9–40.1%, I2 0.689%) of ears 43.5% (CI 33.4–54.2%, I2 0.500) of people.

Conclusion

Tympanic membrane perforation, subjective hearing loss, tinnitus, ear fullness and sensorineural hearing loss are common sequelae of civilian terrorist explosions.

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Acknowledgements

Thanks to Jennifer Manders, Lagojda Lukasz and Gavin Moore, who are clinical evidence-based information specialist librarians who designed and performed the literature search affiliated to the Queen Elizabeth Hospital library and University Hospitals Coventry and Warwickshire library.

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Authors and Affiliations

  1. University of Warwick, University of Warwick Medical School, Coventry, UK

    Luke Debenham & Naairah Khan

  2. University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry, UK

    Luke Debenham & Naairah Khan

  3. London, UK

    Benjamin Nouhan

  4. Department of Ear Nose and Throat Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

    Jameel Muzaffar

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Debenham, L., Khan, N., Nouhan, B. et al. A systematic review of otologic injuries sustained in civilian terrorist explosions. Eur Arch Otorhinolaryngol 281, 2223–2233 (2024). https://doi.org/10.1007/s00405-023-08393-z

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