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Effect of prophylactic central neck dissection on the surgical outcomes in papillary thyroid cancer: experience in a single center

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Abstract

Purpose

Morbidity due to papillary thyroid carcinoma (PTC) is increased mostly due to lymph node (LN) metastases, which lead to reoperations and complications associated with these operations. The aim is to compare the outcomes of PTC having total thyroidectomy and prophylactic central lymph node dissection (TT + PCND) with patients having total thyroidectomy (TT) alone.

Methods

This study is a retrospective cohort analysis of 358 PTC patients that were operated by a single surgeon in a single center. Data about the patients were extracted from the medical records.

Results

Of the patient cohort, 258 patients had TT + PCND (42.5 ± 11.3 years) and 100 patients (41.2 ± 11.9 years) had only TT. Total number of LN extracted in the TT + PCND group was 8.1 ± 6.9. The mean number of metastatic LN were 2.2 ± 1.9. Percentage of patients that had RAI were less in the TT + PCND group compared to the TT group. Seven patients (2.7%) in the TT + PCND group and 19 (19.0%) in TT group had recurrent disease (p < 0.0001). Of the complications, only transient hypoparathyroidism was increased in TT + PCND group compared to TT group (26.7% vs 10%, p < 0.0001).

Conclusion

TT + PCND performed by an experienced surgeon seems to decrease the number of LN recurrences, and the need for reoperations.

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Authors and Affiliations

  1. Section of Endocrinology and Metabolism, Medical School, Koç University, Istanbul, Turkey

    Dilek Yazıcı, Havva Sezer & Faruk Alagöl

  2. Section of Radiology, Amerikan Hospital, Istanbul, Turkey

    Bülent Çolakoğlu

  3. Department of Internal Medicine, Koç University Hospital, Istanbul, Turkey

    Burçin Sağlam

  4. Department of Pathology, Koç University Medical School, Istanbul, Turkey

    Yersu Kapran

  5. Department of Pathology, Faculty of Medicine, Acıbadem Mehmet Ali Aydinlar University, Istanbul, Turkey

    Özlem Aydın

  6. Department of Nuclear Medicine, Koç University Medical School, Istanbul, Turkey

    Mehmet Onur Demirkol

  7. Section of General and Endocrine Surgery, American Hospital, Istanbul, Turkey

    Tarık Terzioğlu

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  1. Dilek Yazıcı
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  2. Bülent Çolakoğlu
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Correspondence to Dilek Yazıcı.

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Yazıcı, D., Çolakoğlu, B., Sağlam, B. et al. Effect of prophylactic central neck dissection on the surgical outcomes in papillary thyroid cancer: experience in a single center. Eur Arch Otorhinolaryngol 277, 1491–1497 (2020). https://doi.org/10.1007/s00405-020-05830-1

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