Skip to main content
Log in

The effect of duration of nasal obstruction on mean platelet volume in patients with marked nasal septal deviation

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Nasal obstruction is a common cause of marked nasal septal deviation. It is related strongly with hypoxia. Hypoxic conditions increase mean platelet volume levels. This study aimed to investigate the effect of age on mean platelet volume in patients with marked nasal septal deviation. We made a retrospective study of patients with marked nasal septal deviation between January 2012 and May 2014. The patients were divided into four groups according to duration of nasal obstruction (less than 10, 10–20, 20–30 and more than 30 years). The groups were compared with each other in terms of mean platelet volume, platelet distribution width, platelet count in preoperative hemogram. This study was performed on 356 male and 139 female patients. Mean age was 33.9 ± 12.3 years. It was determined that the platelet count, mean platelet volume did not constitute statistically significant difference between groups (p > 0.05). Nevertheless, it was determined that as the duration of nasal obstruction elongated the mean platelet volume value increased and platelet count values decreased. Mean values of platelet distribution width constituted statistically significant difference between all groups (p = 0.026). Patients with marked nasal septum deviation should be subjected to surgery as soon as possible because of the increase in mean platelet volume and platelet distribution width values which are related to increase in the risk of cardiopulmonary complications of nasal obstruction.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Jang Y, Yeo N, Wang J (2009) Cutting and suture technique of the caudal septal cartilage for the management of caudal septal deviation. Arch Otolaryngol Head Neck Surg 135:1256–1260. doi:10.1001/archoto.2009.171

    Article  PubMed  Google Scholar 

  2. Proctor DF (1977) The upper airways. I. Nasal physiology and defence of the lungs. Am Rev Respir Dis 115:97–129

    PubMed  CAS  Google Scholar 

  3. Naiboglu B, Deveci S, Duman D, Kaya KS, Toros S, Kinis V et al (2008) Effect of upper airway obstruction on pulmonary arterial pressure in children. Int J Pediatr Otorhinolaryngol 72:1425–1429. doi:10.1016/j.ijporl.2008.06.005

    Article  PubMed  Google Scholar 

  4. Yilmaz MD, Onrat E, Altuntaz A, Kaya D, Kahveci OK, Ozel O et al (2005) The effects of tonsillectomy and adenoidectomy on pulmonary arterial pressure in children. Am J Otolaryngol 26:18–21. doi:10.1016/j.amjoto

    Article  PubMed  Google Scholar 

  5. McNicholas WT (2009) Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease. Am J Respir Crit Care Med 180:692–700. doi:10.1164/rccm.200903-0347PP

    Article  PubMed  CAS  Google Scholar 

  6. Ulu S, Ulu MS, Bucak A, Kahveci OK, Yucedag F, Aycicek A (2013) Evaluating the relationship between nasal obstruction and mean platelet volume by using acoustic rhinometry in patients with septum deviation. Rhinology 51:249–252. doi:10.4193/Rhino12.169

    PubMed  CAS  Google Scholar 

  7. Park Y, Schoene N, Haris W (2002) Mean platelet volume as an indicator of platelet activation: methodological issues. Platelets 13:301–306. doi:10.1080/095371002220148332

    Article  PubMed  CAS  Google Scholar 

  8. Lui MM, Sau-Man M (2012) OSA and atherosclerosis. J Thorac Dis 4:164–172. doi:10.3978/j.issn.2072-1439.2012.01.06

    PubMed  PubMed Central  Google Scholar 

  9. Liak C, Fitzpatrick M (2011) Coagulability in obstructive sleep apnea. Can Respir J 18:338–348

    PubMed  PubMed Central  Google Scholar 

  10. Varol E, Ozturk O, Gonca T, Has M, Ozaydin M, Erdoğan D et al (2010) Mean platelet volume is increased in patients with severe obstructive sleep apnea. Scand J Clin Lab Invest 70:497–502. doi:10.3109/00365513.2010.520733

    Article  PubMed  Google Scholar 

  11. Rahangdale S, Yeh SY, Novack V, Stevenson K, Barnard MR, Furman MI et al (2011) The influence of intermittent hypoxemia on platelet activation in obese patients with obstructive sleep apnea. J Clin Sleep Med 7:172–178

    PubMed  PubMed Central  Google Scholar 

  12. Kisacik B, Tufan A, Kalyoncu U (2008) Mean platelet volume (MPV) as an inflammatory marker in ankylosing spondylitis and rheumatoid arthritis. Joint Bone Spine 75:291–294. doi:10.1016/j.jbspin.2007.06.016

    Article  PubMed  Google Scholar 

  13. Kapsoritakis AN, Koukourakis MI, Sfiridaki A, Potamianos SP, Kosmadaki MG, Koutroubakis IE et al (2001) Mean platelet volume: a useful marker of inflammatory bowel disease activity. Am J Gastroenterol 96:776–781. doi:10.1111/j.1572-0241.2001.03621

    Article  PubMed  CAS  Google Scholar 

  14. Briggs C (2009) Quality counts: new parameters in blood cell counting. IntJ Lab Hematol 31:277–297. doi:10.1111/j.1751-553X.2009.01160.x

    Article  CAS  Google Scholar 

  15. Schoene NW (1997) Design criteria: tests used to assess platelet function. Am J Clin Nutr 65:1665–1668

    Google Scholar 

  16. Sagit M, Korkmaz F, Kavugudurmaz M, Somdas MA (2012) Impact of septoplasty on mean platelet volume levels in patients with marked nasal septal deviation. J Craniofac Surg 23:974–976. doi:10.1097/SCS.0b013e31824e2c08

    Article  PubMed  Google Scholar 

  17. Demirin H, Ozhan H, Ucgun T, Celer A, Bulur S, Cil H et al (2011) Normal range of mean platelet volume in healthy subjects: insight from a large epidemiologic study. Thromb Res 128:358–360. doi:10.1016/j.thromres.2011.05.007

    Article  PubMed  CAS  Google Scholar 

  18. Fidan V, Aksakal E (2011) Impact of septoplasty on pulmonary artery pressure in patients with markedly deviated septum. J Craniofac Surg 22:1591–1593. doi:10.1097/SCS.0b013e31822e5e21

    Article  PubMed  Google Scholar 

  19. Simon P, Sidle D (2012) Augmenting the nasal airway: beyond septoplasty. Am J Rhinol Allergy 26:326–331. doi:10.2500/ajra.2012.26.3786

    Article  PubMed  PubMed Central  Google Scholar 

  20. Brodsky L, Poje C (1998) Tonsillitis, Tonsillectomy and Adenoidectomy. In: Bailey JB, Calhoun KH, Deksin RW (eds) Head and Neck Surgery-Otolaryngology, 2nd edn. Lippincott Raven Press, Philadelphia, pp 1221–1235

    Google Scholar 

  21. Olson EJ, Park JG, Morgenthaler TI (2005) Obstructive sleep apnea-hypopnea syndrome. Prim Care 32:329–359. doi:10.1016/j.pop.2005.02.007

    Article  PubMed  Google Scholar 

  22. Von Kanel R, Dimsdale JE (2003) Hemostatic alterations in patients with obstructive sleep apnea and the implications for cardiovascular disease. Chest 124:1956–1967. doi:10.1378/chest.124.5.1956

    Article  Google Scholar 

  23. Varol E, Dogan A, Erdogan D, Ozaydin M, Peker RO (2012) Septoplasty decreases mean platelet volume levels in patients with marked nasal septal deviation. J Craniofac Surg 23:1938. doi:10.1097/SCS.0b013e318271021c

    Article  PubMed  Google Scholar 

  24. Kucur C, Kulekci S, Zorlu A, Savran B, Oghan F, Yildirim N (2014) Mean platelet volume levels in children with adenoid hypertrophy. J Craniofac Surg 25:29–31. doi:10.1097/SCS.0b013e3182a2eddd

    Article  Google Scholar 

Download references

Conflict of interest

The authors report that there are no potential conflicts of interest relevant to this article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ilhan Unlu.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Unlu, I., Kesici, G.G., Oneç, B. et al. The effect of duration of nasal obstruction on mean platelet volume in patients with marked nasal septal deviation. Eur Arch Otorhinolaryngol 273, 401–405 (2016). https://doi.org/10.1007/s00405-015-3580-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-015-3580-2

Keywords

Navigation