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Effect of Deviated Nasal Septum on Mean Platelet Volume: A Prospective Study

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Abstract

Nasal obstruction due to Deviated Nasal Septum (DNS) is a commonly encountered condition by the Otorhinolaryngologist. This leads to chronic hypoxia which in turn leads to stimulation of platelets. This change can be assessed by estimation of the Mean Platelet Volume (MPV) which is a commonly available investigation while ordering a haemogram. As there is a lot of conflicting data about the relationship between DNS and MPV, this study was undertaken to evaluate if there is a relationship between these two parameters. A 1-year observational study was done and after adhering to the inclusion and exclusion criteria, there were 50 cases of deviated nasal septum and 50 controls who attended the ENT Out-Patient Department of a tertiary care hospital who were evaluated. Blood was drawn and the Mean Platelet Volume was estimated. It was found that there was no statistical significance between the cases and controls. Contradictory to other studies done in literature, our study did not find any correlation. This could be due to the type of septal deviation cases that were part of our study. Hence, multicentric studies with larger samples need to be studied in order to establish sound conclusions.

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Authors and Affiliations

  1. Department of ENT and Head & Neck Surgery, KAHER’s J. N. Medical College, Belagavi, Karnataka, India

    Nitin R. Ankle, Rohini Desai & Rajesh Radhakrishna Havaldar

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  1. Nitin R. Ankle
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  2. Rohini Desai
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  3. Rajesh Radhakrishna Havaldar
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Correspondence to Rajesh Radhakrishna Havaldar.

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Written informed consent was obtained from the relatives/ legal guardians of the study participant.

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 Approval was obtained from the ethics committee of KLE Academy of Higher Education and Research. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

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Ankle, N.R., Desai, R. & Havaldar, R.R. Effect of Deviated Nasal Septum on Mean Platelet Volume: A Prospective Study. Indian J Otolaryngol Head Neck Surg 74 (Suppl 2), 1216–1219 (2022). https://doi.org/10.1007/s12070-020-02289-8

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  • DOI: https://doi.org/10.1007/s12070-020-02289-8

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