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Altering of lower critical solution temperature of environmentally responsive poly (N-isopropylacrylamide-co-acrylic acid-co-vanillin acrylate) affected by acrylic acid, vanillin acrylate, and post-polymerization modification

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Abstract

For the improvement of poly (N-isopropylacrylamide) properties, new series of poly (N-isopropylacrylamide-Co-acrylic acid-Co-vanillin acrylate) terpolymer was fabricated with molar concentrations 5, 10, and 15 mol% of acrylic acid (AA) with 10 mol% of vanillin acrylate (VA). Monomer and polymers were chemically evaluated using (1H NMR, 13C, FT-IR, and UV); all structures emphasized logical results. The post-polymerization has been done for terpolymer with tryptophan and threonine; they were chemically investigated. Polymers and post-polymers have been physically characterized using SEM, X-ray, DSC, TGA, and SEM. Lower critical solution temperature was measured using turbidity by UV–VIS spectroscopy and by micro-DSC. These polymers will be used in the post-polymerization of many biomolecules for biomedical applications

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Acknowledgements

We would like to thank the Paderborn University.

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Authors and Affiliations

  1. Polymer Lab, Department of Chemistry, Faculty of Science (Assiut), Al-Azhar University, Assiut, 71524, Egypt

    Momen S. A. Abdelaty

  2. Polymer Lab, Department of Chemistry, Faculty of Science, University of Tabuk, 71491, Tabuk, Saudi Arabia

    Momen S. A. Abdelaty

  3. Department of Chemistry, Paderborn University, Warburger Straße 100, 33098, Paderborn, Germany

    Dirk Kuckling

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Abdelaty, M.S.A., Kuckling, D. Altering of lower critical solution temperature of environmentally responsive poly (N-isopropylacrylamide-co-acrylic acid-co-vanillin acrylate) affected by acrylic acid, vanillin acrylate, and post-polymerization modification. Colloid Polym Sci 299, 1617–1629 (2021). https://doi.org/10.1007/s00396-021-04882-x

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