Abstract
All processes involved in metal homeostasis must be coordinated to provide sufficient, but not toxic, concentrations of important bioelements, and to minimize detrimental effects of toxic metals. Our previous studies dealing with the exposure of O. nubilalis non-diapausing larvae to dietary Cd demonstrated that exposure to higher concentrations of Cd caused delay in the development of larvae, induced oxidative stress and also induced defense mechanisms against the toxic effects of Cd. The aim of the present study was to evaluate how acute and chronic exposure of O. nubilalis larvae to increased concentrations of dietary Cd affected the balance of important bioelements. The concentration of bioelements was analyzed in larvae (after short-term exposure) and pupae (after long-term exposure). The short-term exposure of final instar larvae (L5) to Cd did not affect significantly the concentration of any of the analyzed bioelements, while the long-term exposure of developing larvae to higher concentrations of Cd caused increase in the concentrations of Ca, Mg and Na in pupae. The bioaccumulation factor, calculated for bioelements after long-term exposure to Cd, was higher for the most bioelements in groups fed with diet containing higher concentrations of Cd, except K which displayed the opposite trend. Pearson correlation coefficient showed positive correlations between Cd and Ca, Mg, Na, Fe, Cu and Zn, while negative correlation was observed between Cd and K. The results indicate that impact on the balance of important bioelements might be one of the mechanisms of cadmium toxicity and certainly raise numerous questions for future research.
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Acknowledgements
Authors are thankful to Dr. Filip Franeta for providing biological material (O. nubilalis egg masses from the corn field), as well as for valuable and constructive suggestions during the planning and development of this research work.
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The authors acknowledge financial support of the Ministry of Education, Science and Technological Development of the Republic of Serbia [Grant No. 451-03-68/2022–14/200125].
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JP, ELV and TVC designed the study. Material preparation and analysis were performed by DK, SO, SM and JV. ELV and TVC statistically analyzed data. The first draft of the manuscript was written by TVC and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Čelić, T.V., Vukašinović, E.L., Kojić, D. et al. Exposure to High Concentrations of Cadmium Which Delay Development of Ostrinia Nubilalis Hbn. Larvae Affected the Balance of Bioelements. Arch Environ Contam Toxicol 83, 193–200 (2022). https://doi.org/10.1007/s00244-022-00953-4
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DOI: https://doi.org/10.1007/s00244-022-00953-4