Die Normalisierung Genetisch Bedingter Defekte der Zelltrennung beiParamaecium aurelia Durch Sauerstoffmangel und Kohlenmonoxyd

Summary

Of two strains ofParamecium aurelia Syngen4, one differs from the normal form by a gene-induced cytpolasmic mutation (Mo-strain), the other by a simple gene mutation (snaky). Both strains have a very similar character: the cells fail to separate with a variable frequency and monster formation results (Table 1).

The phenotype of the two strains can be completely normalised by low oxygen tension (Table 2) or by the presence of carbon monoxide. The CO effect is reversible by light (Table 3, 4). 2,4-Dinitrophenol reduces the frequency of monster formation, sometimes to zero (Table 5). Iodoacetic acid, on the other hand, causes a tenfold increase in monster formation over the controls under certain conditions (Table 6).

The facts are discussed in relation to the Pasteur phenomenon.