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Effect of aminoglycoside antibiotics on the autolytic enzyme of Streptomyces griseus

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Abstract

The isolated cell wall of Streptomyces griseus 52–1 strain labelled with fluorescein isothiocyanate (FITC) and containing wall-bound autolytic enzyme was lysed as a function of different cations. The autolysis was accelerated by aminoglycoside antibiotics (streptomycin and the structurally closely related neomycin) which have a polycationic character. Since this strain is a streptomycin producer it is suggested that streptomycin may have a regulatory function on autolysis.

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Szabó, I., Penyige, A., Barabás, G. et al. Effect of aminoglycoside antibiotics on the autolytic enzyme of Streptomyces griseus . Arch. Microbiol. 155, 99–102 (1990). https://doi.org/10.1007/BF00291282

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  • DOI: https://doi.org/10.1007/BF00291282

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