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The Regulation of Vascular Endothelial Biology by Frow

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Cell Mechanics and Cellular Engineering

Abstract

The inner surface of a blood vessel is composed of a monolayer of vascular endothelial cells which serves as the interface with flowing blood. Once thought to be simply a passive, non-thrombogenic barrier, the vascular endothelium is now recognized as being a dynamic participant in the biology of a blood vessel (Kaiser and Sparks 1987). Part of its dynamic character is due to the regulation of the biology of the endothelium by the mechanical environment associated with the hemodynamics of the vascular system.

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Authors
  1. R. M. Nerem
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  2. P. R. Girard
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  3. G. Helmlinger
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  4. O. Thoumine
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  5. T. F. Wiesner
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  6. T. Ziegler
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Editor information

Editors and Affiliations

  1. Orthopaedic Research Laboratory, Columbia University, 630 W. 168th Street, New York, NY, 10032, USA

    Van C. Mow

  2. Department of Aerospace Engineering, Mechanics and Engineering Science, University of Florida, Gainesville, FL, 32611, USA

    Roger Tran-Son-Tay

  3. Musculo-Skeletal Research Laboratory, Department of Orthopaedics, Health Science Center, State University of New York, Stony Brook, NY, 11794, USA

    Farshid Guilak

  4. Department of Mechanical Engineering and Material Sciences, Duke University, Durham, NC, 27708, USA

    Robert M. Hochmuth

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Nerem, R.M., Girard, P.R., Helmlinger, G., Thoumine, O., Wiesner, T.F., Ziegler, T. (1994). The Regulation of Vascular Endothelial Biology by Frow. In: Mow, V.C., Tran-Son-Tay, R., Guilak, F., Hochmuth, R.M. (eds) Cell Mechanics and Cellular Engineering. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8425-0_5

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