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Endometrial Regenerative Cells and Exosomes Thereof for Treatment of Radiation Exposure

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Regenerative Medicine

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Abstract

In 2007, we discovered a novel subset of mesenchymal stem cells (MSCs) derived from the endometrium, termed “endometrial regenerative cells (ERC).” In comparison to other MSC types (e.g., bone marrow and adipose), ERC possess (a) more rapid proliferative rate, (b) higher levels of growth factor production (VEGF, GM-CSF, PDGF), and (c) higher angiogenic activity. We are currently running two clinical trials for these cells in patients with critical limb ischemia and heart failure.

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Authors and Affiliations

  1. Biotechnology Division, Cromos Pharma, 4027 Oak Street, Longview, WA, 98632, USA

    Vladimir Bogin MD

  2. Regen BioPharma, 5700 Spring Street, La Mesa, CA, 92942, USA

    Thomas E. Ichim

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  1. Vladimir Bogin MD
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  2. Thomas E. Ichim
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Correspondence to Thomas E. Ichim .

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Editors and Affiliations

  1. Calcutta School of Tropical Medicine, Kolkata, India

    Niranjan Bhattacharya

  2. Boston University School of Medicine, Jamaica Plain, Massachusetts, USA

    Phillip George Stubblefield

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Bogin, V., Ichim, T.E. (2015). Endometrial Regenerative Cells and Exosomes Thereof for Treatment of Radiation Exposure. In: Bhattacharya, N., Stubblefield, P. (eds) Regenerative Medicine. Springer, London. https://doi.org/10.1007/978-1-4471-6542-2_4

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  • DOI: https://doi.org/10.1007/978-1-4471-6542-2_4

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