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Aortic Stenosis

  • Chapter
Neonatal Heart Disease

Abstract

Critical aortic valve stenosis presenting in the neonatal period is clearly a unique entity with pathology, clinical features and prognosis all of which stand apart from left ventricular outflow tract obstruction seen in later life (Table 22.1). In large measure this is due to the considerable overlap that exists in the pathology of critical aortic stenosis in the neonate and the so-called hypoplastic left heart syndrome as described by Noonan and Nadas [47]. This relationship between aortic stenosis and the hypoplastic left heart syndrome disappears rapidly after the first month of life owing to the high mortality rates for both critical aortic stenosis and the hypoplastic left heart syndrome in this age period. It is rare for either supravalvar or the relatively discrete subvalvar forms of aortic stenosis to present in the neonatal period. In contrast to the spectrum of disease seen in the older child the site of obstruction in the newborn is valvar almost without exception [33]. This chapter therefore will deal primarily with valvar aortic stenosis with only a brief discussion of the Williams-Beuren syndrome and of mechanisms of subaortic stenosis.

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References

Aortic Stenosis, Valvar

  1. Angelini A, Ho SY, Anderson RH, (1989) The morphology of the normal aortic valve as compared with the aortic valve having two leaflets. J Thorac Cardiovasc Surg 98: 362–367

    PubMed  CAS  Google Scholar 

  2. Bass JL, Berry JM, Einzig S (1986) Flow in the aorta and patent ductus arteriosus in infants with aortic atresia or aortic stenosis: a pulsed doppler study. Circulation 74: 315–322

    Article  PubMed  CAS  Google Scholar 

  3. Berman W Jr, Yabek SM, Fripp RR, Burstein R, Dillon T, Corlew S (1988) Medical management of three asymptomatic infants with severe valvar aortic stenosis. Pediatr Cardiol 9: 237–242

    Article  PubMed  Google Scholar 

  4. Bernhard WF, Keane JF, Fellows KE, Litwin SB, Gross RE (1973) Progress and problems in the management of critical aortic stenosis. J Thorac and Cardiovasc Surg 66: 404–419

    CAS  Google Scholar 

  5. Brown JW, Robison RC, Waller BF (1985) Transventricular balloon catheter aortic valvotomy in neonates. Ann Thorac Surg 39: 376–378

    Article  PubMed  CAS  Google Scholar 

  6. Burrows PE, Benson LN, Williams WG et al. (1990) Iliofemoral arterial complications of balloon angioplasty for systemic obstructions in infants and children. Circulation 82: 1697–1704

    Article  PubMed  CAS  Google Scholar 

  7. Campbell M, Kauntze R (1953) Congenital aortic valvular stenosis. Br Heart J 15: 179–190

    Article  PubMed  CAS  Google Scholar 

  8. de la Cruz MV, Munoz-Castellanos L, Nadal-Ginard B (1971) Extrinsic factors in the genesis of congenital heart disease. Br Heart J 33: 203–213

    Article  PubMed  Google Scholar 

  9. Dobell AR, Bloss RS, Gibbons JE, Collins GF (1981) Congenital valvular aortic stenosis surgical management and long term results. J Thorac Cardiovasc Surg 81: 916–920

    PubMed  CAS  Google Scholar 

  10. Duncan K, Sullivan I, Robinson MB, Horvath P, de Leval M, Stark J (1987) Transventricular aortic valvotomy for critical aortic stenosis in infants. J Thorac Cardiovasc Surg 93: 546–550

    PubMed  CAS  Google Scholar 

  11. Dyck JD, Coles JC, Benson LN, Williams WG, Trusler GA (1988) Attempts to improve results with critical aortic stenosis in the neonate (abstr). Circulation 78 (Suppl II): 970

    Google Scholar 

  12. Edmunds LH, Wagner HR, Heymann MA (1980) Aortic valvotomy in neonates. Circulation 61: 421–427

    PubMed  Google Scholar 

  13. Edwards JE. (1965) Pathology of left ventricular outflow tract obstruction. Circulation 31: 586–599

    PubMed  CAS  Google Scholar 

  14. Emanuel R, Withers R, O’Brien K, Ross P, Feizi O (1978) Congenitally bicuspid aortic valve. Br Heart J 40: 1402–1407

    Article  PubMed  CAS  Google Scholar 

  15. Fishman WH, Hof RB, Rudolph AM, Heymann MA (1978) Models of congenital heart disease in fetal lambs. Circulation 58: 354–361

    PubMed  CAS  Google Scholar 

  16. Freedom RM (1989) Balloon therapy of critical aortic stenosis in the neonate. The therapeutic conundrum resolved? Circulation 80: 1087–1088

    Article  PubMed  CAS  Google Scholar 

  17. Fyler DC (1980) Report of the New England Regional Infant Cardiac Program. Pediatrics (suppl) 65: 388–417

    Google Scholar 

  18. Giddens NG, Finley JP, Nanton MA, Roy DL (1989) The natural course of supravalvar aortic stenosis and peripheral pulmonary artery stenosis in William’s syndrome. Br Heart J 62: 315–319

    Article  Google Scholar 

  19. Giloni SH (1973) Cardiac malformations in the chick embryo induced by thalidomide. Toxicol Appl Pharmacol 25: 77–83

    Article  Google Scholar 

  20. Graham TP Jr, Jarmakani JM, Canent RV, Morrow MN (1971) Left heart volume estimation in infancy and childhood: revaluation of methodology and normal values. Circulation 43: 895–904

    PubMed  Google Scholar 

  21. Grant RP (1962) The morphogenesis of transposition of the great vessels. Circulation 26: 818–840

    Google Scholar 

  22. Greene DG, Carlisle R, Grant C, Bunnell IL (1967) Estimation of LV volume by single plane cineangiography. Circulation 35: 61–69

    PubMed  CAS  Google Scholar 

  23. Gundry SR, Behrendt DM (1986) Prognostic factors in valvotomy for critical aortic stenosis in infancy. J Thorac Cardiovasc Surg 92: 747–754

    PubMed  CAS  Google Scholar 

  24. Hagler DJ, Tajik AJ, Seward JB, Ritter DG (1986) Noninvasive assessment of pulmonary valve stenosis, aortic valve stenosis, and coarctation of the aorta in critically ill neonates. Am J Cardiol 57: 369–372

    Article  PubMed  CAS  Google Scholar 

  25. Hammon JW, Lupinetti FM, Maples MD et al. (1988) Predictors of operative mortality in congenital valvular aortic stenosis present in infancy. Ann Thorac Surg 45: 532–540

    Article  Google Scholar 

  26. Harh JY, William JG, Friedberg DZ, Kaplan S (1973) Experimental production of hypoplastic left heart syndrome in the chick embryo. Am J Cardiol 31: 51–56

    Article  PubMed  CAS  Google Scholar 

  27. Haring OM (1966) Cardiac malformations in the rat induced by maternal hypercapnia with hypoxia. Circ Res 195: 445–451

    Google Scholar 

  28. Hastreiter AR, Oshima M, Miller RA, Lev M, Paul MH (1963) Congenital aortic stenosis syndrome in infancy. Circulation 28: 1084–1095

    PubMed  CAS  Google Scholar 

  29. Hoffman JIE (1989) Aortic stenosis. In: Moller JH, Neal WA (eds) Fetal, neonatal, and infant cardiac disease. Appleton and Lange, Norwalk, CT pp 451–473

    Google Scholar 

  30. Huhta, JC, Latson LA, Gutgesell HP, Cooly DA, Kearney DL (1984) Echocardiography in the diagnosis and management of symptomatic aortic valve stenosis in infants. Circulation 70: 438–444

    Article  PubMed  CAS  Google Scholar 

  31. Huhta JC, Carpenter RJ, Moise KJ, Deter RL, Ott DA, McNamara DC (1987) Prenatal diagnosis and postnatal management of critical aortic stenosis. Circulation 75: 573–576

    Article  PubMed  CAS  Google Scholar 

  32. Johnson RG, Williams GR, Razook JD, Thompson WM, Lane MM, Elkins RC (1987) Reoperation in congenital aortic stenosis. Ann Thorac Surg 42: 156–162

    Google Scholar 

  33. Kasten-Sportes CH, Piechaud J-F, Sidi D, Kachaner J (1989) Percutaneous balloon valvuloplasty in neonates with critical aortic stenosis. J Am Coll Cardiol 13: 1101–1105

    Article  PubMed  CAS  Google Scholar 

  34. Keane JF, Bernhard WF, Nadas AS (1975) Aortic stenosis surgery in infancy. Circulation 52: IBS-IMS

    Google Scholar 

  35. Keith JD, Rowe RD, Vlad P (1967) Heart disease in infancy and childhood, 2nd edn. MacMillan, Publishing Co, New York, pp 252–254

    Google Scholar 

  36. Kugler JD, Campbell E, Vargo TA, McNamara DG, Hallman GL, Cooley DA (1979) Results of aortic valvotomy in infants with isolated aortic valve stenosis. J Thorac Cardiovasc Surg 78: 553–558

    PubMed  CAS  Google Scholar 

  37. Lababidi Z, Weinhaus L (1986) Successful balloon valvuloplasty for neonatal critical aortic stenosis. Am Heart J 112: 913–915

    Article  PubMed  CAS  Google Scholar 

  38. Lakier JB, Lewis AB, Heymann MA, Stanger P, Hoffman Jl, Rudolph AM (1974) Isolated aortic stenosis in the neonate. Circulation 50: 801–808

    PubMed  CAS  Google Scholar 

  39. Lambert EC, Canent RV, Hohn AR (1966) Congenital Cardiac Anomalies in the newborn: a review of conditions causing death or severe distress in the first month of life. Pediatrics 37: 343–348

    PubMed  CAS  Google Scholar 

  40. Latson LA, Cheatham JP, Gutgesell HP (1981) Relation of the echo estimate of left ventricular size to mortality in infants with severe left ventricular outflow obstruction. Am J Cardiol 48: 887–891

    Article  PubMed  CAS  Google Scholar 

  41. Lev M (1952) Pathologic anatomy and interrelationships of hypoplasia of the aortic tract complexes. Lab Invest 1: 61–70

    PubMed  CAS  Google Scholar 

  42. Lev M, Arcilla R, Rimoldi HJA, Licata RH, Gasul BM (1962) Premature narrowing or closure of the foramen ovale. Am Heart J 65: 638–647

    Article  Google Scholar 

  43. Marquis RM, Logan A (1955) Congenital aortic stenosis and its surgical treatment. Br Heart J 17: 373–378

    Article  PubMed  CAS  Google Scholar 

  44. Messina LM, Turley K, Stanger P, Hoffman JIE, Ebert PA (1984) Successful aortic valvotomy for severe congenital valvular aortic stenosis in the newborn infant. J Thorac Cardiovasc Surg 88: 92–96

    PubMed  CAS  Google Scholar 

  45. Mocellin R, Sauer U, Simon B, Comazzi M, Sebening F, Buhlmeyer K (1983) Reduced left ventricular size and endocardial fibroelastosis as correlates of mortality in newborns and young infants with severe aortic valve stenosis. Pediatr Cardiol 4: 265–272

    Article  PubMed  CAS  Google Scholar 

  46. Mody MR, Nadas AS, Bernhard WF (1967) Aortic stenosis in infants. N Engl J Med 276: 832–837

    Article  PubMed  CAS  Google Scholar 

  47. Moller JH, Nakib A, Edwards JE (1966) Infarction of papillary muscles and mitral insufficiency associated with congenital aortic stenosis. Circulation 34: 87–91

    PubMed  CAS  Google Scholar 

  48. Noonan JA, Nadas AS (1958) Hypoplastic left heart syndrome: an analysis of 101 cases. Pediatr Clin North Am 5: 1029–1035

    PubMed  CAS  Google Scholar 

  49. Nora JJ, Nora AH (1978) Genetics and counselling in cardiovascular diseases. CC Thomas Publisher Springfield, Illinois, p 175

    Google Scholar 

  50. Parsons MK, Moreau GA, Graham TB (1988) Echocardiographic determination of critical left ventricular sizein infantile aortic stenosis (abstr) Circulation 78, (Suppl II): 395

    Google Scholar 

  51. Pelech AN, Dyck JD, Trusler GA, Williams WG, Olley PM, Freedom RM (1987) Critical aortic stenosis: survival and management. J Thorac Cardiovasc Surg 94: 510–517

    PubMed  CAS  Google Scholar 

  52. Perry SB, Zeevi B, Keane JF, Lock JE, (1989) Interventional catheterization of left heart lesions, including aortic and mitral valve stenosis and coarctation of the aorta. Cardiol Clin vol 7: 341–350

    PubMed  CAS  Google Scholar 

  53. Presbitero P, Somerville J, Revel-Chion R, Ross D (1982) Open aortic valvotomy for congenital aortic stenosis: late results. Br Heart J 47: 26–34

    Article  PubMed  CAS  Google Scholar 

  54. Roberts WC (1970) The structure of the aortic valve in clinically isolated aortic stenosis. Circulation 42: 91–97

    PubMed  CAS  Google Scholar 

  55. Robertson MA, Byrne PJ, Penkoske PA (1989) Perinatal management of critical aortic valve stenosis diagnosed by fetal echocardiography. Br Heart J 61: 365–367

    Article  PubMed  CAS  Google Scholar 

  56. Rowe RD, Freedom RM, Mehrizi A (1981) The neonate with congenital heart disease. WB Saunders, New York, pp 562–576

    Google Scholar 

  57. Rupprath G, Neuhaus KL (1987) Percutaneous balloon valvuloplasty for aortic valve stenosis in infancy. Am J Cardiol 55: 943–947

    Google Scholar 

  58. Sandqr GS, Olley PM, Trusler GA, Williams WG, Rowe RD, Morch JE (1980) Long term follow up of patients after congenital valvular aortic stenosis in children. J Thorac and Cardiovasc Surg 80: 171–176

    Google Scholar 

  59. Sholler GF, Keane JF, Stanton BP, Sanders SP, Lock JE (1988) Balloon dilatation of congenital aortic valve stenosis. Circulation 78: 351–360

    Article  PubMed  CAS  Google Scholar 

  60. Shone JD, Sellers RD, Anderson RC, Adams P, Lillehei CW, Edwards JE (1963) The developmental complex of “parachute” mitral valve, supravalvular ring of left atrium, subaortic stenosis and coarctation of the aorta. Am J Cardiol 11: 714–725

    Article  PubMed  CAS  Google Scholar 

  61. Sink JD, Smallhorn JF, Macartney FJ, Taylor JFN, Stark J, de Leval MR (1984) Management of critical aortic stenosis in infancy. J Thorac Cardiovasc Surg 588: 92–96

    Google Scholar 

  62. Strasburger JF, Kugler JD, Cheatham JP, McManus BM (1984) Nonimmunologic hydrops fetalis associated with congenital aortic valve stenosis. Am Heart J 108: 1380–1382

    Article  PubMed  CAS  Google Scholar 

  63. Tandon R, Moller JH, Edwards JE (1986) Anomalies associated with the parachute mitral valve: a pathologic analysis of 52 cases. Can J Cardiol 2: 278–281

    PubMed  CAS  Google Scholar 

  64. Trinkle JK, Norton JB, Richardson JD, Grover FL, Noonan JA (1975) Closed aortic valvotomy and simultaneous correction of associated anomalies in infants. J Thorac Cardiovasc Surg 69: 758–762

    PubMed  CAS  Google Scholar 

  65. Turley K, Bove E, Amato J et al. (1990) Neonatal aortic stenosis. J Thorac Cardiovasc Surg 99: 679–684

    PubMed  CAS  Google Scholar 

  66. Van Praagh R, Bano-Rodrigo A, Smolinsky A, Schuetz TJ, Fyler DC, Van Praagh S (1986) Anatomic variations in congenital valvar, subvalvar, and supravalvar aortic stenosis: a study of 64 postmortem cases. In: Takahashim Wells WJ, Lindesmith EE (eds) Challenges in the treatment of congenital cardiac anomalies. Futura, Mount Kisco, New York, pp 13–41

    Google Scholar 

  67. Williams WG, Rebeyka IM, Tibshirani RJ et al. (1990) Warm induction blood cardioplegia in the infant: a technique to avoid rapid cooling myocardial contracture. J Thorac Cardiovasc Surg 100: 896–901

    PubMed  CAS  Google Scholar 

  68. Wren C, Sullivan J, Bull C, Deanfield J (1987) Percutaneous balloon dilatation of aortic valve stenosis in neonates and infants. Br Heart J 58: 608–612

    Article  PubMed  CAS  Google Scholar 

  69. Zeevi B, Keane JF, Castaneda AR, Perry SB, Lock JE (1989) Neonatal critical aortic stenosis. A comparison of surgical and balloon dilatation therapy. Circulation 80: 831–839

    Google Scholar 

Supravalvar Aortic Stenosis

  1. Beitzke A, Becker H, Rigler B, Stein JI, Suppan C (1986) Development of aortic aneurysms in familial supravalvular aortic stenosis. Pediatr Cardiol 6: 227–229

    Article  PubMed  CAS  Google Scholar 

  2. Beuren AJ, Apitz J, Harmjanz D (1962) Supravalvar aortic stenosis in association with mental retardation and certain facial appearance. Circulation 26: 1235–1240

    PubMed  CAS  Google Scholar 

  3. Black JA, Bonham Carter RE (1963) Association between aortic stenosis and facies of severe infantile hypercalcaemia. Lancet ii: 745–749

    Google Scholar 

  4. Bleiden LC, Lucas RV Jr, Carter JB, Miller K, Edwards JE (1974) A developmental complex including supravalvular stenosis of the aorta and pulmonary trunk. Circulation 49: 585–590

    Google Scholar 

  5. Burn J (1986) William’s syndrome. J Med Genet 23: 389–395

    Article  PubMed  CAS  Google Scholar 

  6. Ensing GJ, Schmidt MA, Hagler DJ, Michels VV, Carter GA, Feldt RH (1989) Spectrum of findings in a family with nonsyndromic autosomal dominant supravalvular aortic stenosis: a Doppler echocardiographic study. J Am Coll Cardiol 13: 413–419

    Article  PubMed  CAS  Google Scholar 

  7. Giddens HG, Finley JD, Hanton MA, Roy DL (1989) The natural course of supravalvar aortic stenosis and peripheral artery stenosis in William’s syndrome. Br Heart J 62: 315–319

    Article  Google Scholar 

  8. Hallidie-Smith KA, Karas S (1988) Cardiac anomalies in Williams-Beuren syndrome. Arch Dis Child 63: 809–813

    Article  PubMed  CAS  Google Scholar 

  9. Ino T, Nishimoto N, Iwahara M et al. (1988) Progressive vascular lesions in Williams-Beuren syndrome. Pediatr Cardiol 9: 55–58

    Article  PubMed  CAS  Google Scholar 

  10. Williams JCP, Barratt-Boyes BG, Lowe JB (1961) Supravalvar aortic stenosis. Circulation 24: 1311–1318

    PubMed  CAS  Google Scholar 

  11. Wren C, Oslizlok P, Bull C (1990) Natural history of supravalvular aortic stenosis and pulmonary artery stenosis. J Am Coll Cardiol 15: 1625–1630

    Article  PubMed  CAS  Google Scholar 

  12. Yamaguchi Y, Tachibana H, Hosokawa K, Ohashi H, Imai I (1987) Staged repair of supravalvar aortic stenosis associated with severe multiple peripheral pulmonary stenoses. J Thorac Cardiovasc Surg 93: 785–793

    PubMed  CAS  Google Scholar 

  13. Zalstein E, Moes CAF, Musewe NN, Freedom RM (1989) The spectrum of cardiovascular anomalies in Williams-Beuren syndrome (abstr). Presented at Canadian Cardiovascular Society Meeting, Vancouver, Oct. 1989.

    Google Scholar 

Subvalvular Aortic Stenosis

  1. Baumstark A, Fellows KE, Rosenthal A (1978) Combined double chambered right ventricle and discrete subaortic stenosis. Circulation 57: 299–303

    PubMed  CAS  Google Scholar 

  2. Becu LM, Tauxe WN, Du Shane JW, Edwards JE (1955) A complex of congenital cardiac anomalies: ventricular septal defect, biventricular origin of the pulmonary trunk and subaortic stenosis. Am Heart J 50: 901–911

    Article  PubMed  CAS  Google Scholar 

  3. Bjork VO, Hultquist G, Lodin H (1961) Subaortic stenosis produced by an abnormally placed anterior mitral leaflet. J Thorac Cardiovasc Surg 41: 659–669

    Google Scholar 

  4. Chung KJ, Fulton DR, Kreidberg MB, Payne DD, Cleveland RJ (1984) Combined discrete subaortic stenosis and ventricular septal defect in infants and children. Am J Cardiol 53: 1429–1432

    Article  PubMed  CAS  Google Scholar 

  5. Copperberg P, Hazell S, Ashmore PG (1976) Parachute accessory anterior mitral valve leaflet causing left ventricular outflow tract obstruction. Circulation 53: 908–911

    Google Scholar 

  6. Feigl A, Lucas RV Jr, Edwards JE (1984) Involvement of the aortic valve cusps in discrete subaortic stenosis. Pediatr Cardiol 5: 185–190

    Article  PubMed  CAS  Google Scholar 

  7. Feigl D, Feigl A, Sweetman KM, Lobo FV, Moller JH, Edwards JE (1986) Accessory tissue of the tricuspid valve protruding into the left ventricle through a septal defect. Arch Pathol Lab Med 110: 144–147

    PubMed  CAS  Google Scholar 

  8. Feldman T, Chiu Y, Carroll J (1987) Catheter balloon dilatation of discrete subaortic stenosis in the adult. Am J Card 60: 403–405

    Article  PubMed  CAS  Google Scholar 

  9. Fisher DJ, Snider AR, Silverman NH, Stanger P (1982) Ventricular septal defect with silent discrete subaortic stenosis. Pediatr Cardiol 2: 265–269

    Article  PubMed  CAS  Google Scholar 

  10. Freedom RM, Bain HH, Esplugas E, Dische R, Rowe RD (1977) Ventricular septal defect in interruption of aortic arch. Am J Cardiol 39: 572–582

    Article  PubMed  CAS  Google Scholar 

  11. Freedom RM, Culham JAG, Rowe RD (1977) Angiocardiography of subaortic obstruction in infancy. Am J Roentgenol 129: 813–824

    CAS  Google Scholar 

  12. Freedom RM, Dische MR, Rowe RD (1977) Conal anatomy in aortic atresia, ventricular septal defect and normally developed left ventricle. Am Heart J 94: 689–698

    Article  PubMed  CAS  Google Scholar 

  13. Freedom RM, Dische MR, Rowe RD (1977) Pathological anatomy of subaortic stenosis and atresia in the first year of life. Am J Cardiol 39: 1035–1044

    Article  PubMed  CAS  Google Scholar 

  14. Freedom RM, Fowler RS, Duncan WJ (1981) Rapid evolution from “normal” left ventricular outflow tract to fatal subaortic stenosis in infancy. Br Heart J 45: 605–609

    Article  PubMed  CAS  Google Scholar 

  15. Freedom RM, Culham JAG, Moes CAF (1984) Angiocardiography of congenital heart disease. Mac-millan Publishing Co, New York, pp 369–404

    Google Scholar 

  16. Freedom RM, Pelech A, Brand A et al. (1985) The progressive nature of subaortic stenosis in congenital heart disease. Int J Cardiol 8: 137–143

    Article  PubMed  CAS  Google Scholar 

  17. Gomes AS, Nath PH, Singh A et al. (1980) Accessory flaplike tissue causing ventricular outflow obstruction. J Thorac Cardiovasc Surg 80: 211–216

    PubMed  CAS  Google Scholar 

  18. Gutgesell HP, Mullins CE, Gillette PC, McNamara DC (1976) Transient subaortic stenosis of infants of diabetic mothers. J Pediatr 89: 120–125

    Article  PubMed  CAS  Google Scholar 

  19. Katz NM, Buckley MJ, Liberthson RR (1977) Discrete membranous subaortic stenosis. Circulation 56: 1034–1038

    PubMed  CAS  Google Scholar 

  20. Keane JF, Fellows KE, LaFarge CG, Nadas AS, Bernhard WF (1976) The surgical management of discrete and diffuse supravalvar aortic stenosis. Circulation 54: 112–117

    PubMed  CAS  Google Scholar 

  21. Kelly DT, Wulfsberg E, Rowe RD (1972) Discrete subaortic stenosis. Circulation 46: 309–322

    PubMed  CAS  Google Scholar 

  22. Khan MM, Varma MPS, Cleland J (1981) Discrete subaortic stenosis. Br Heart J 46: 421–431

    Article  PubMed  CAS  Google Scholar 

  23. Labibidi Z, Weinhaus L, Stoeckle H, Walls J (1987) Transluminal balloon dilatation for discrete subaortic stenosis. Am J Cardiol 59: 423–425

    Article  Google Scholar 

  24. Lauer RM, Du Shane JW, Edwards JE (1960) Obstruction of left ventricular outlet in association with ventricular septal defect. Circulation 22: 110–125

    PubMed  CAS  Google Scholar 

  25. Leichter DA, Sullivan I, Gersony WM (1989) “Acquired” discrete subvalvular aortic stenosis: natural history and hemodynamics. J Am Cell Cardiol 14: 1539–1544

    Google Scholar 

  26. Mace S, Hirshfield SS, Riggs T, Fanaroff AA, Merkatz IR (1979) Echocardiographic abnormalities in infants of diabetic mothers. J Pediatr 95: 1013–1019

    Article  PubMed  CAS  Google Scholar 

  27. Maron BJ, Edwards JE, Henry WL, Clark CE, Bingle GJ, Epstein SE (1974) Asymetric septal hypertrophy ( ASH) in infancy. Circulation 50: 809–820

    Google Scholar 

  28. Maron BJ, Tajik AJ, Ruttenberg HD et al. (1982) Hypertrophic cardiomyopathy in infants: clinical fea-tures and natural history. Circulation 65: 7–17

    Article  PubMed  CAS  Google Scholar 

  29. Mody MR, Mody GT (1975) Serial hemodynamic observations in congenital valvular and subvalvular aortic stenosis. Am Heart J 89: 137–143

    Article  PubMed  CAS  Google Scholar 

  30. Moene RJ, Oppenheimer-Dekker A, Wenink ACG (1981) Relation between aortic arch hypoplasia of variable severity and central muscular ventricular septal defects: emphasis on associated left ventricular abnormalities. Am J Cardiol 48: 111–116

    Article  PubMed  CAS  Google Scholar 

  31. Moene RJ, Oppenheimer-Dekker A, Moulaert AJ, Wenink ACG, Gittengerger-de Groot AC, Roozendaal H (1982) The concurrence of dimensional aortic arch anomalies and abnormal left ventricular muscle bundles. Pediatr Cardiol 2: 107–114

    Article  PubMed  CAS  Google Scholar 

  32. Morais P, Westaby S, Hallidie-Smith KA (1986) Left ventricular outflow tract obstruction due to anomalous mitral valve: successful mitral valve replacement in a four month old infant. Br Heart J 56: 385–387

    Article  PubMed  CAS  Google Scholar 

  33. Moulaert AJ, Bruins CC, Oppenheimer-Dekker A (1976) Anomalies of the aortic arch and ventricular septal defects. Circulation 53: 1011–1015

    PubMed  CAS  Google Scholar 

  34. Nanton MA, Belcourt CL, Gillis DA, Krause VW, Roy DL (1979) Left ventricular outflow tract obstruction owing to accessory endocardial cushion tissue. J Thorac Cardiovasc Surg 78: 537–541

    PubMed  CAS  Google Scholar 

  35. Newfeld EA, Muster AJ, Paul MH, Idriss FS, Riker WL (1976) Discrete subvalvular aortic stenosis in childhood. Study of 51 patients. Am J Cardiol 38: 53–60

    Article  PubMed  CAS  Google Scholar 

  36. Penkoske PA, Collins-Nakai RL, Duncan NF (1989) Subaortic stenosis in childhood: frequency of associated anomalies and surgical options, J Thorac Cardiovasc Surg 98: 852–860

    PubMed  CAS  Google Scholar 

  37. Pyle RL, Patterson DF, Chacko S (1976) The genetics and pathology of discrete subaortic stenosis in the Newfoundland dog. Am Heart J 92: 324–334

    Article  PubMed  CAS  Google Scholar 

  38. Rosenquist GC, Clark EB, Sweeney LJ, McAllister HA (1976) The normal spectrum of mitral and aortic valve discontinuity. Circulation 54: 298–301

    PubMed  CAS  Google Scholar 

  39. Rosenquist GC, Clark EB, McAllister HA, Bharati S, Edwards JE (1979) Increased mitral-aortic separation in discrete subaortic stenosis. Criculation 60: 70–74

    CAS  Google Scholar 

  40. Rosenthal A, Freed MD, Fyler DC, Litwin SB (1974) Observations on the development of subaortic stenosis following pulmonary artery banding. Chest 65: 420–423

    Article  PubMed  CAS  Google Scholar 

  41. Schaffer M, Freedom RM, Rowe RD (1983) Hypertrophic cardiomyopathy presenting before 2 years of age in 13 patients. Pediatr Cardiol 4: 113–117

    Article  PubMed  CAS  Google Scholar 

  42. Schneeweiss A, Motro M, Shem-Tov A, Blieden LC, Neufeld HN (1983) Discrete subaortic stenosis associated with congenital valvular aortic stenosis -A diagnostic challenge. Am Heart J 106: 55–63

    Article  PubMed  CAS  Google Scholar 

  43. Sellers RD, Lillehei CW, Edwards JE (1964) Subaortic stenosis caused by anomalies of the atrioventricular valves. J Thorac Cardiovasc Surg 48: 289–302

    PubMed  CAS  Google Scholar 

  44. Shem-Tov A, Schneeweiss A, Motro M, Neufeld HN (1982) Clinical presentation and natural history of mild discrete subaortic stenosis. Follow-up of 1–17 years. Circulation 66: 509–512

    Article  PubMed  CAS  Google Scholar 

  45. Shone JD, Sellers RD, Anderson RC, Adams P Jr, Lillehei CW, Edwards JE (1963) The developmental complex of “parachute mitral valve”, supravalvular ring of the left atrium, subaortic stenosis, and coarctation of the aorta. Am J Cardiol 11: 714–725

    Article  PubMed  CAS  Google Scholar 

  46. Shore DF, Smallhorn J, Stark J, Lincoln C, de Leval MR (1982) Left ventricular outflow tract obstruction co-existing with ventricular septal defects. Br Heart J 48: 421–427

    Article  PubMed  CAS  Google Scholar 

  47. Smallhorn JF, Anderson RH, Macartney FJ (1983) Morphological characterisation of ventricular septal defects associated with coarctation of aorta by cross-sectional echocardiography. Br Heart J 49: 485–494

    Article  PubMed  CAS  Google Scholar 

  48. Somerville J (1979) Congenital heart disease-changes in form and function. Br Heart J 41: 1–22

    Article  PubMed  CAS  Google Scholar 

  49. Somerville J (1985) Fixed subaortic stenosis -a frequently misunderstood lesion. Int J Cardiol 8: 145–148

    Article  Google Scholar 

  50. Van Praagh R, Corwin RD, Dahlquist Jr EH, Freedom RM, Mattioli L, Nebesar RA (1970) Tetralogy of Fallot with severe left ventricular outflow tract obstruction due to anomalous attachment of the mitral valve to the ventricular septum. Am J Cardiol 26: 93–101

    Article  PubMed  Google Scholar 

  51. Vogel M, Freedom RM, Brand A, Trusler GA, Williams WG, Rowe RD (1983) Ventricular septal defect and subaortic stenosis: an analysis of 41 patients. Am J Cardiol 52: 1258–1263

    Article  PubMed  CAS  Google Scholar 

  52. Vogel M, Smallhorn JF, Freedom RM, Coles J, Williams WG, Trusler GA (1988) The association of ventricular septal defect and anomalous right ventricular muscle bundles with fixed subaortic stenosis. An echocardiography study of 36 patients. Am J Cardiol 61: 857–862

    Article  PubMed  CAS  Google Scholar 

  53. Way GL, Wolfe RR, Eshaghpour E, Bender RL, Jaffe RB, Ruttenberg HD (1979) The natural history of hypertrophic cardiomyopathy in infants of diabetic mothers. J Pediatr 95: 1020–1025

    Article  PubMed  CAS  Google Scholar 

  54. Wright GB, Keane JF, Nadas AS, Bernhard WF, Castaneda AR (1983) Fixed subaortic stenosis in the young: medical and surgical course in 83 patients. Am J Cardiol 52: 830–835

    Article  PubMed  CAS  Google Scholar 

  55. Zielinsky P, Rossi M, Haertel JC, Vitola D, Lucchese FA, Rodrigues R (1987) Subaortic fibrous ridge and ventricular septal defect: role of septal malalignment. Circulation 75: 1124–1129

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. J. D. Dyck
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  2. R. M. Freedom
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© 1992 Springer-Verlag London Limited

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Dyck, J.D., Freedom, R.M. (1992). Aortic Stenosis. In: Neonatal Heart Disease. Springer, London. https://doi.org/10.1007/978-1-4471-1814-5_22

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  • DOI: https://doi.org/10.1007/978-1-4471-1814-5_22

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1816-9

  • Online ISBN: 978-1-4471-1814-5

  • eBook Packages: Springer Book Archive

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