Abstract
Latina women with prior gestational diabetes mellitus (GDM) are at elevated risk for type 2 diabetes mellitus and cardiovascular disease. Few primary prevention programs are designed for low socioeconomic status, Spanish-speaking populations. We examined the effectiveness of a Diabetes Prevention Program (DPP) translation in low-income Latinas with a history of GDM. Eighty-four Latinas, 18–45 years old with GDM in the past 3 years, underwent an 8-week peer-educator-led group intervention, with tailoring for Latino culture and recent motherhood. Lifestyle changes and diabetes and cardiovascular risk factors were assessed at study baseline, month 3 and month 6. Participants showed significant improvements in lipids, blood pressure, physical activity, dietary fat intake, and fatalistic and cultural diabetes beliefs (p < 0.05). Formative evaluation provides preliminary evidence of program acceptability. A peer-led, culturally appropriate DPP translation was effective in improving lifestyle changes and some indicators of cardiovascular and diabetes risk in Latinas with GDM.
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REFERENCES
Bellamy L, Casas JP, Hingorani AD, Williams D. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet. 2009;373(9677):1773-1779.
Di Cianni G, Ghio A, Resi V, Volpe L. Gestational diabetes mellitus: an opportunity to prevent type 2 diabetes and cardiovascular disease in young women. Womens Health. 2010;6(1):97-105.
US Center for Health Statistics. Births: final data for 2008. Natl Vital Stat Rep. 2010;59(1):3-71.
Ferrara A. Increasing prevalence of gestational diabetes mellitus. Diabetes Care. 2007;30(Supplement 2):S141-S146.
Cowie CC, Rust KF, Ford ES, et al. Full accounting of diabetes and pre-diabetes in the US population in 1988–1994 and 2005–2006. Diabetes Care. 2009;32(2):287-294.
Kjos SL, Peters RK, Xiang A, Henry OA, Montoro M, Buchanan TA. Predicting future diabetes in Latino women with gestational diabetes. Utility of early postpartum glucose tolerance testing. Diabetes. 1995;44(5):586-591.
Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346(6):393-403.
Diabetes Prevention Program Research Group, Knowler WC, Fowler SE, et al. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program outcomes study. Lancet. 2009;374(9702):1677-1686.
Ratner R, Goldberg R, Haffner S, et al. Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program. Diabetes Care. 2005;28(4):888-894.
The Diabetes Prevention Program Outcomes Study Research Group. Long-term effects of the Diabetes Prevention Program interventions on cardiovascular risk factors: a report from the DPP Outcomes Study. Diabet Med. 2013;30(1):46-55.
Jackson L. Translating the diabetes prevention program into practice. Diabetes Educ. 2009;35(2):309-320.
Ali MK, Echouffo-Tcheugui JB, Williamson DF. How effective were lifestyle interventions in real-world settings that were modeled on the Diabetes Prevention Program? Health Aff. 2012;31(1):67-75.
Ferrara A, Ehrlich SF. Diabetes prevention interventions for women with a history of GDM. In: Kim C, Ferrara A, eds. Gestational diabetes during and after pregnancy. London: Springer; 2010:361-372.
Ferrara A, Hedderson MM, Albright CL, et al. A pregnancy and postpartum lifestyle intervention in women with gestational diabetes mellitus reduces diabetes risk factors: a feasibility randomized control trial. Diabetes Care. 2011;34(7):1519-1525.
Bentley-Lewis R. Gestational diabetes mellitus: an opportunity of a lifetime. Lancet. 2009;373(9677):1738-1740.
Ratner RE, Christophi CA, Metzger BE, et al. Prevention of diabetes in women with a history of gestational diabetes: effects of metformin and lifestyle interventions. J Clin Endocrinol Metab. 2008;93(12):4774-4779.
Ockene IS, Tellez TL, Rosal MC, et al. Outcomes of a Latino community-based intervention for the prevention of diabetes: the Lawrence Latino Diabetes Prevention Project. Am J Public Health. 2012;102(2):336-342.
Castro FG, Shaibi GQ, Boehm-Smith E. Ecodevelopmental contexts for promoting exercise for preventing diabetes among racial/ethnic minority populations. J Behav Med. 2009;32(1):89-105.
Caballero AE. Understanding the Hispanic/Latino patient. Am J Med. 2011;124:S10-S15.
Ayala GX, Vaz L, Earp JA, Elder JP, Cherrington A. Outcome effectiveness of the lay health advisor model among Latinos in the United States: an examination by role. Health Educ Res. 2010;25(5):815-840.
Rhodes SD, Foley KL, Zometa CS, Bloom FR. Lay health advisor interventions among Hispanics/Latinos: a qualitative systematic review. Am J Prev Med. 2007;33(5):418-427.
American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2013;36(Supplement 1):S67-S74.
Bandura A. Health promotion by social cognitive means. Health Educ Behav. 2004;31(2):143-164.
Bandura A. Social learning theory. Englewood Cliffs, NJ: Prentice-Hall; 1977.
Bandura A. Self-efficacy: the exercise of control. New York: Freeman; 1997.
Warnick GR. Measurement of cholesterol and other lipoprotein constituents in the clinical laboratory. Clin Chem Lab Med. 2000;38(4):287-300.
Neeley WE. Simple automated determination of serum or plasma glucose by a hexokinase/glucose-6-phosphate dehydrogenase method. Clin Chem. 1972;18(6):509-515.
Chobanian AV, Bakris GL, Black HR, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003;289(19):2560-2572.
Block G, Gillespie C, Rosenbaum EH, Jenson C. A rapid food screener to assess fat and fruit and vegetable intake. Am J Prev Med. 2000;18(4):284-288.
Block G, Hartman AM, Dresser CM, Carroll MD, Gannon J, Gardner L. A data-based approach to diet questionnaire design and testing. Am J Epidemiol. 1986;124(3):453-469.
Elder JP, Ayala GX, Campbell NR, et al. Interpersonal and print nutrition communication for a Spanish-dominant Latino population: secretos de la buena vida. Health Psychol. 2005;24(1):49-57.
Topolski TD, LoGerfo J, Patrick DL, Williams B, Walwick J, Patrick MB. The rapid assessment of physical activity (RAPA) among older adults. Prev Chron Dis. 2006;3(4):A118.
Powe BD. Fatalism among elderly African Americans. Effects on colorectal cancer screening. Cancer Nurs. 1995;18(5):385-392.
Lopez-McKee G, McNeill JA, Eriksen LR, Ortiz M. Spanish translation and cultural adaptation of the Powe Fatalism Inventory. J Nurs Scholarsh. 2007;39(1):68-70.
Philis-Tsimikas A, Walker C, Rivard L, et al. Improvement in diabetes care of underinsured patients enrolled in project dulce: a community-based, culturally appropriate, nurse case management and peer education diabetes care model. Diabetes Care. 2004;27(1):110-115.
Corporation IBM. IBM SPSS Statistics for Windows, Version 20.0. Armonk, NY: IBM Corp.; 2011.
Raudenbush SW, Bryk AS, Congdon R. HLM 6 for Windows. Lincolnwood, IL: Scientific Software International; 2004.
Enders CK. Applied missing data analysis. New York: Guilford; 2010.
Philis-Tsimikas A, Fortmann A, Lleva-Ocana L, Walker C, Gallo LC. Peer-led diabetes education programs in high-risk Mexican Americans improve glycemic control compared with standard approaches: a Project Dulce promotora randomized trial. Diabetes Care. 2011;34(9):1926-1931.
The Lipid Research Clinics Coronary Primary Prevention Trial results. II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA. 1984; 251(3): 365–374.
Colhoun HM, Betteridge DJ, Durrington PN, et al. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet. 2004;364(9435):685-696.
Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. JAMA. 1998;279(20):1615-1622.
Estruch R, Ros E, Salas-Salvadó J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013;368(14):1279-1290.
Investigators HOPES. Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators. Lancet. 2000;355(9200):253-259.
Pedersen TR, Olsson AG, Faergeman O, et al. Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S). Circulation. 1998;97(15):1453-1460.
Cook NR, Cohen J, Hebert PR, Taylor JO, Hennekens CH. Implications of small reductions in diastolic blood pressure for primary prevention. Arch Intern Med. 1995;155(7):701-709.
Diabetes Prevention Program Work Group. Impact of intensive lifestyle and Metformin therapy on cardiovascular disease risk factors in the Diabetes Prevention Program. Diabetes Care. 2005;28(4):888-894.
Feathers JT, Kieffer EC, Palmisano G, et al. The development, implementation, and process evaluation of the REACH Detroit Partnership’s diabetes lifestyle intervention. Diabetes Educ. 2007;33(3):509-520.
Rosal M, Lemon S, Nguyen O, Driscoll N, DiTaranto L. Translation of the diabetes prevention program lifestyle intervention for promoting postpartum weight loss among low-income women. Transl Behav Med. 2011;1(4):530-538.
Cole-Lewis H, Kershaw T. Text messaging as a tool for behavior change in disease prevention and management. Epidemiol Rev. 2010;32(1):56-69.
Bennett GG, Glasgow RE. The delivery of public health interventions via the Internet: actualizing their potential. Annu Rev Public Health. 2009;30:273-292.
Goode AD, Reeves MM, Eakin EG. Telephone-delivered interventions for physical activity and dietary behavior change: an updated systematic review. Am J Prev Med. 2012;42(1):81-88.
Bennett GG, Warner ET, et al. Obesity treatment for socioeconomically disadvantaged patients in primary care practice. Arch Intern Med. 2012;172(7):565-574.
Bentley-Lewis R. Late cardiovascular consequences of gestational diabetes mellitus. Semin Reprod Med. 2009;27(4):322-329.
Acknowledgments
The current research was supported by grants 1 U01 RR025774 and 5 UL1 RR025774 from the National Institutes of Health/National Center for Advancing Translational Sciences (NCATS). The authors thank the staff and participants of the Dulce Mothers study for their important contributions.
Trial Registration
The trial has been registered with Clinicaltrials.gov—Community Approach to Reduce the Risks of Diabetes After Gestational Diabetes Mellitus, NCT01613937, 06/05/2012
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Implications
Practice: A low cost, clinically effective and culturally appropriate Diabetes Prevention Program translation for Latinas with a recent history of gestational diabetes mellitus was feasible, acceptable, and reduced some aspects of diabetes and cardiovascular disease risk.
Policy: Programs such as Dulce Mothers may promote policy changes to extend Medicaid/Medicare health care coverage for women with a gestational diabetes mellitus diagnosis to 1-year postdelivery and to cover prevention/education interventions for high-risk populations.
Research: The postgestational diabetes mellitus population is an important target for prevention and research given exceptionally high risk for future type 2 diabetes mellitus and cardiovascular disease.
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Philis-Tsimikas, A., Fortmann, A.L., Dharkar-Surber, S. et al. Dulce Mothers: an intervention to reduce diabetes and cardiovascular risk in Latinas after gestational diabetes. Behav. Med. Pract. Policy Res. 4, 18–25 (2014). https://doi.org/10.1007/s13142-014-0253-4
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DOI: https://doi.org/10.1007/s13142-014-0253-4