Abstract
A novel Candida glycerinogenes mutant, which possesses high glycerol productivity in a high phosphate concentration medium, was obtained by mutagenesis of an industrial glycerol producer. The mutant accumulated a total biomass of 11.5 g l−1, which is less than the 15 g l−1of the wild-type strain, but it consumed glucose faster than the wild-type strain did. The mutant reached its maximal glycerol concentration of 129 g l−1 in 84 h compared to 96 h for the wild-type strain. High cytoplasmic glycerol-3-phosphate dehydrogenase activity of the mutant in the early glycerol formation phase, leading to a rapid glycerol synthesis and accumulation, may be the main reason for the short fermentation process.
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Zhuge, B., Guo, XN., Mawadza, C. et al. A novel Candida glycerinogenes mutant with high glycerol productivity in high phosphate concentration medium. World J Microbiol Biotechnol 21, 453–456 (2005). https://doi.org/10.1007/s11274-004-1879-z
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DOI: https://doi.org/10.1007/s11274-004-1879-z