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A New Schiff Base Chemodosimeter for Fluorescent Imaging of Ferric Ions in Living Cells

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Abstract

A new and efficient chemodosimeter for ferric ions has been developed. The visual and fluorescent behaviors of the compound toward various metal ions were investigated: ferric ions are distinguished from other cations by selective color change and unusual fluorescence enhancement in mixed aqueous solution. Fluorescence microscopy experiments showed that this receptor is effective for detection of Fe3+ in vitro, developing a good image of the biological organelles. The sensing mechanism is shown to involve a hydrolysis process.

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Acknowledgments

We thank the Ministry of Science and Technology, Taiwan, R.O.C., for the financial support.

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Authors and Affiliations

  1. Providence University, Taichung City, Taiwan, Republic of China

    Yan-Zi Chen, Yeshwant Ramchandra Bhorge, Albert J. Pape, Rupesh D. Divate, Yun-Chin Chung & Yao-Pin Yen

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  1. Yan-Zi Chen
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  2. Yeshwant Ramchandra Bhorge
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  3. Albert J. Pape
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  4. Rupesh D. Divate
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  5. Yun-Chin Chung
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  6. Yao-Pin Yen
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Correspondence to Yao-Pin Yen.

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Chen, YZ., Bhorge, Y.R., Pape, A.J. et al. A New Schiff Base Chemodosimeter for Fluorescent Imaging of Ferric Ions in Living Cells. J Fluoresc 25, 1331–1337 (2015). https://doi.org/10.1007/s10895-015-1622-1

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  • DOI: https://doi.org/10.1007/s10895-015-1622-1

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