Abstract
Expression of markers, collagens, and HLA-1 by human skin fibroblasts and fibroblast-like cells isolated from the umbilical Wharton’s jelly was compared. Skin fibroblasts express collagens (proteins characteristic of differentiated cells of this histogenetic series) and HLA-1, while umbilical cells express, in addition to collagens, juvenile surface markers and almost no HLA-1. This indicates that fibroblast-like cells isolated from different sources are different and can serve as sources for the creation of cell preparations with different characteristics in future.
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Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 1, pp. 53–59, January, 2006
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Yarygin, K.N., Suzdal’tseva, Y.G., Burunova, V.V. et al. Comparative study of adult human skin fibroblasts and umbilical fibroblast-like cells. Bull Exp Biol Med 141, 161–166 (2006). https://doi.org/10.1007/s10517-006-0117-0
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DOI: https://doi.org/10.1007/s10517-006-0117-0