Abstract
Pathogens like helminths, viruses, and bacteria infect a significant number of people throughout the world. The evolution of parasites with humans has enabled them to envisage effective strategies for their long-term survival in hosts. Such long-term existence of these pathogens is often precarious to the human body. The chronic inflammation and immunomodulation caused by these pathogens also induces oxidative stress at the site of infection. Chronic inflammation is significantly recognized for cancer initiation and development. If pathogenic infection is untreated, such prolonged inflammation and increased oxidative stress can cause cancer. This chapter summarizes the different types of cancers induced by pathogens specifically with respect to the oxidative stress induced by these pathogens. Furthermore, this chapter also highlights the use of natural and synthetic antioxidants as an effective therapeutic strategy to circumvent the oxidative stress caused by pathogens and subsequently hinder the progression of cancer.
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Khatri, V., Munirathinam, G., Kalyanasundaram, R. (2022). Pathogens and Cancer. In: Chakraborti, S. (eds) Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-16-1247-3_184-1
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DOI: https://doi.org/10.1007/978-981-16-1247-3_184-1
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