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Phosphatidylinositol (3)-Monophosphate in Plants

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Encyclopedia of Lipidomics

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Synonyms

PI3P; PtdIns(3)P

Definition

Phosphoinositides :

all phosphorylated forms of phosphatidylinositol

Glycerophospholipid :

a lipid composed of glycerol, two fatty acids attached to the sn-1 and sn-2 position of this glycerol, and a head group attached to the sn-3 position via a phosphate

Abundance and Synthesis

Phosphatidylinositol-3-monophosphate (PI3P) is a glycerophospholipid with an inositol ring as the head group, which is esterified to a phosphate group at the D3 position of the inositol ring. Due to the density of negative charges at the polar head group of the molecule, PI3P can be considered a strong epitope in cellular membranes that can function as an attachment site for proteins (Hammond and Balla 2015).

The very hydrophilic head group combined with the hydrophobic acyl chains as well as the low abundance makes it difficult to analyze PI3P. Silanized glassware has to be used throughout extraction, transfer, and storage, as phosphoinositides stick to metals and...

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Abbreviations

ATP:

Adenosine triphosphate

FAB1:

Forms Aploid and Binucleate cells

PCCP:

Predicted C2 domain-containing protein

PI(3,5)P2 :

Phosphatidylinositol (3, 5)-bisphosphate

PI3P:

Phosphatidylinositol-3-monophosphate

PI4P:

Phosphatidylinositol-4-monophosphate

PTEN:

Phosphatase and tensin homolog

VPS:

Vacuolar protein sorting

References

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Author information

Authors and Affiliations

  1. Albrecht-von-Haller-Institute for Plant Sciences, Department of Plant Biochemistry, Georg-August-University Goettingen, Justus-von-Liebig-Weg 11, D-37077, Goettingen, Germany

    Krzysztof Zienkiewicz & Till Ischebeck

Authors
  1. Krzysztof Zienkiewicz
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  2. Till Ischebeck
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Corresponding author

Correspondence to Krzysztof Zienkiewicz .

Editor information

Editors and Affiliations

  1. Yong Loo Lin School of Medicine Centre for Life Sciences, Singapore, Singapore

    Markus R. Wenk

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Zienkiewicz, K., Ischebeck, T. (2017). Phosphatidylinositol (3)-Monophosphate in Plants. In: Wenk, M. (eds) Encyclopedia of Lipidomics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7864-1_151-2

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  • DOI: https://doi.org/10.1007/978-94-007-7864-1_151-2

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-7864-1

  • Online ISBN: 978-94-007-7864-1

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Chapter history

  1. Latest

    Phosphatidylinositol (3)-Monophosphate in Plants
    Published:
    25 September 2017

    DOI: https://doi.org/10.1007/978-94-007-7864-1_151-2

  2. Original

    Phosphatidylinositol (3)-Monophosphate in Plants
    Published:
    30 March 2017

    DOI: https://doi.org/10.1007/978-94-007-7864-1_151-1

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