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Keimzelltumoren bei Kindern und Jugendlichen

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Kinderchirurgie

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Zusammenfassung

Keimzelltumoren des Kindes sind Tumoren, deren Ursprung auf primordiale Keimzellen zurückgeführt wird. Das biologische Verhalten von Keimzelltumoren wird ganz wesentlich vom Alter des Patienten, Geschlecht, Tumorsitz, Histologie, aber auch Zytogenetik und Molekularbiologie beeinflusst. Keimzelltumoren umfassen ein breites Spektrum von Entitäten mit unterschiedlicher Klinik, Histologie und Biologie. Keimzelltumoren können maligne oder benigne sein, letzteres meist mit einem malignen Potenzial. Unterschieden werden extrakranielle Keimzelltumoren der Geschlechtsdrüsen (gonadal) von Tumoren anderer Lokalisation (extragonadal). Die Behandlung von Keimzelltumoren erfolgt überwiegend innerhalb multizentrischer prospektiver Therapiestudien. Diagnostik und Therapie intrakranieller Keimzelltumoren gehorchen besonderen Regeln und sind nicht Gegenstand dieses Kapitels (Plant et al. 2016, Pediatric malignant germ cell tumors: a comparison of the neuro-oncology and solid tumor experience. Pediatr Blood Cancer 63:2086–2095).

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Authors and Affiliations

  1. Klinik für Kinderchirurgie, Marienhospital Herne, St. Elisabeth Gruppe, Ruhr-Universität Bochum, Herne, Deutschland

    Ralf-Bodo Tröbs

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  1. Ralf-Bodo Tröbs
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Correspondence to Ralf-Bodo Tröbs .

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Editors and Affiliations

  1. Kinderchirurgische Klinik und Poliklinik, Klinikum der Universität München Kinderchirurgische Klinik und Poliklinik, München, Bayern, Germany

    Dietrich von Schweinitz

  2. Abt. Kinderchirurgie, Medizinische Hochschule Hannover (MHH) Kinderklinik, Hannover, Germany

    Benno Ure

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Tröbs, RB. (2018). Keimzelltumoren bei Kindern und Jugendlichen. In: von Schweinitz, D., Ure, B. (eds) Kinderchirurgie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53390-1_89-1

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  • DOI: https://doi.org/10.1007/978-3-662-53390-1_89-1

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  • Print ISBN: 978-3-662-53390-1

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