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Burn Infections

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The Prokaryotes

Abstract

Burns are a common and devastating form of trauma. The incidence of burns worldwide severe enough to require medical attention in 2004 was nearly 11 million people, and ranked fourth in all injuries. Recent data from the USA estimate that approximately 450,000 upwards to 1.1 million burn injuries occurs per annum based on visits to hospital emergency departments. Moderate to severe burn injuries requiring hospitalization account for approximately 45,000 of these cases, of which 20,000 are major burns involving ≥25 % of the total body surface area. Based on selected statistics for admissions to Burn Centers in the USA, the overall survival rate from burn injury was 94.8 % in the past decade (2000–2009). Improved survival is attributed to medical advances in fluid resuscitation; nutritional support; pulmonary care; burn wound care, particularly early excision and wound closure; and use of modern infection control practices. Although approximately 3,500–4,500 patients currently die each year as a direct result of their burn injury, up to 10,000 patients die from burn-related infections, particularly sepsis from burn wound infection, or other sources often associated with inhalation injury. This chapter reviews our current understanding of the mechanism, pathogenesis, immune response, diagnosis, management, and prevention of burn wound infections.

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Authors and Affiliations

  1. Departments of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada

    Dr. Deirdre L. Church

  2. Departments of Medicine, University of Calgary, Calgary, AB, Canada

    Dr. Deirdre L. Church

  3. Departments of Critical Care, University of Calgary, Calgary, AB, Canada

    Ingrid Slaba & Brent W. Winston

  4. Departments of Surgery, Faculty of Medicine, University of Calgary, Calgary, AB, Canada

    Robert Lindsay

  5. Division of Microbiology, Calgary Laboratory Services, 9-3535 Research Rd. N.W., Calgary, AB, Canada

    Dr. Deirdre L. Church

Authors
  1. Dr. Deirdre L. Church
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  2. Ingrid Slaba
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  3. Brent W. Winston
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  4. Robert Lindsay
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Corresponding author

Correspondence to Deirdre L. Church .

Editor information

Editors and Affiliations

  1. Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel

    Eugene Rosenberg

  2. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA

    Edward F. DeLong

  3. Department of Microbiology and Immunology, Harvard Medical School, Boston, MA, USA

    Stephen Lory

  4. Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany

    Erko Stackebrandt

  5. Laboratory of Microbiology, Institute of Biology, Center for Health Sciences, Federal University of Rio de Janeiro (UFRJ), Ilha do Fundão, Rio de Janeiro, Brazil

    Fabiano Thompson

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© 2013 Springer-Verlag Berlin Heidelberg

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Church, D.L., Slaba, I., Winston, B.W., Lindsay, R. (2013). Burn Infections. In: Rosenberg, E., DeLong, E.F., Lory, S., Stackebrandt, E., Thompson, F. (eds) The Prokaryotes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30144-5_102

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