Skip to main content

Virology

  • Living reference work entry
  • First Online:
Encyclopedia of Cancer
  • 65 Accesses

Definition

Virology addresses the molecular nature of viruses, their genetic content, the pathway by which they enter cells and multiply using the molecular machinery of the host cell, and the mechanisms by which they elicit diseases. Tumor virology is a specialized discipline analyzing the association of particular virus types with cancers in animals and humans.

Characteristics

In 1964 the first human tumor virus, the Epstein–Barr virus (EBV), was isolated from tumor samples of a patient with African Burkitt lymphoma. Subsequently, EBV was linked to the development of other forms of cancer. In the 44 years since the discovery of EBV, other human tumor viruses have been identified (Table 1).

Table 1 Major oncogenic viruses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Cullen BR (2006) Viruses and microRNAs. Nat Genet 38(Suppl):S25–S30

    Article  CAS  PubMed  Google Scholar 

  • Khan G (2006) Epstein-Barr virus, cytokines, and inflammation: a cocktail for the pathogenesis of Hodgkin’s lymphoma? Exp Hematol 34:399–406

    Article  CAS  PubMed  Google Scholar 

  • Poulin DL, DeCaprio JA (2006) Is there a role for SV40 in human cancer? J Clin Oncol 24:4356–4365

    Article  CAS  PubMed  Google Scholar 

  • Stanley MA (2006) Human papillomavirus vaccines. Rev Med Virol 16:139–149

    Article  PubMed  Google Scholar 

  • Tao Q, Young LS, Woodman CB et al (2006) Epstein-Barr virus (EBV) and its associated human cancers–genetics, epigenetics, pathobiology and novel therapeutics. Front Biosci 11:2672–2713

    Article  CAS  PubMed  Google Scholar 

See Also

  • (2012) Humanized antibodies. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 1760. doi: 10.1007/978-3-642-16483-5_2863

    Google Scholar 

  • (2012) Monoclonal antibody. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 2367. doi: 10.1007/978-3-642-16483-5_6842

    Google Scholar 

  • (2012) Monoclonal antibody therapy. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, pp 2367–2368. doi: 10.1007/978-3-642-16483-5_3823

    Google Scholar 

  • (2012) P53. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 2747. doi: 10.1007/978-3-642-16483-5_4331

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Paul G. Murray .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Murray, P.G. (2015). Virology. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_6195-2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-27841-9_6195-2

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Publish with us

Policies and ethics