Table 1 Major oncogenic viruses
From: Virology
Virus family | Virus | Natural host | Host in which virus is oncogenic | Tumor | Major oncogenic protein(s) |
|---|---|---|---|---|---|
Adenoviridae | Human adenoviruses A, B, D | Man | Hamster, rat | Various | E1A, E1B |
Polyomaviridae | Polyoma | Mouse | Mouse | Various | Middle T antigen, large T antigen |
SV40 | Monkey | Hamster, rat | Various | Large T antigen | |
Papillomaviridae | HPV 16,18 | Man | Man | Skin cancer, cervical cancer, anal cancer | E6, E7 |
Herpesviridae | EBV | Man | Man | Burkitt lymphoma, nasopharyngeal carcinoma, Hodgkin lymphoma | LMP1 |
KSHV | Man | Man | Kaposi sarcoma, multicentric Castleman disease, primary effusion lymphoma | Â | |
Hepadnaviridae | Hepatitis B virus | Man | Man | Hepatocellular carcinoma | Hepatitis B x antigen |
Flaviviridae | Hepatitis C virus | Man | Man | Hepatocellular carcinoma | HCV core, NS3, NS4B, NS5A |
Retroviridae | HTLV1 | Man | Man | Adult T cell leukemia | Tax |