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Sebaceous Physiology

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Agache's Measuring the Skin

Abstract

The sebaceous gland is a holocrine system composed of acini and excretory ducts and different cell layers, which produce sebum. The rate and pattern of sebum excretion differ throughout different stages of life. Sebum has various functions in humans and its development is affected by different factors such as steroid synthesis, growth factors, hormones, etc. Sebocytes, the components of sebaceous glands, synthesize and store lipids. Sebum is unique in some aspects and differs in composition with other lipids. It is also species-specific. Different immortalized sebaceous gland cell lines have been produced for usage in research studies. Sebocytes produce hormones and are affected by hormones and other factors; different types of receptors play major roles in processes involving sebocytes of sebaceous glands.

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Authors and Affiliations

  1. Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran

    Alireza Firooz, Hamed Zartab & Ali Rajabi-Estarabadi

  2. Tissue Engineering and Wound Healing Lab, Department of Surgery, Division of Plastic Surgery, Brigham and Women’s Hospital – Harvard Medical School, Boston, USA

    Hamed Zartab

Authors
  1. Alireza Firooz
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  2. Hamed Zartab
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  3. Ali Rajabi-Estarabadi
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Corresponding author

Correspondence to Alireza Firooz .

Editor information

Editors and Affiliations

  1. Department of Dermatology, University Hospital of Besançon, Besançon, France

    Philippe Humbert

  2. Center for Study and Research on the Integuments, Department of Dermatology, University Hospital of Besançon, Besançon, France

    Ferial Fanian

  3. Department of Dermatology, School of Medicine, University of California, San Francisco, California, USA

    Howard I. Maibach

  4. Department of Dermatology, University Hospital of Besançon, Besançon, France

    Pierre Agache

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Firooz, A., Zartab, H., Rajabi-Estarabadi, A. (2017). Sebaceous Physiology. In: Humbert, P., Fanian, F., Maibach, H., Agache, P. (eds) Agache's Measuring the Skin. Springer, Cham. https://doi.org/10.1007/978-3-319-32383-1_13

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  • DOI: https://doi.org/10.1007/978-3-319-32383-1_13

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