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Irisflorentin: Advances on Resources, Metabolism, and Pharmacological Activities

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Handbook of Dietary Flavonoids

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Abstract

Irisflorentin, a common plan-derived natural flavonoid, is one of the major bioactive constituents of plants from Iridaceae family, especially famous traditional Chinese herb Belamcanda chinensis. Since irisflorentin was first reported in 1973, the researches on this compound have lasted for almost 50 years, which ranged from isolation, identification, qualitative and quantitative analysis and methods development, metabolism properties to various bioactivities evaluation and studies on the mechanism of action. In this regard, many isolation and analysis methods developed for irisflorentin have been applied to the quality control for irisflorentin-rich traditional Chinese medicines and related Chinese patent medicine. Meanwhile, irisflorentin was also reported to possess anti-inflammatory, antitumor, antidiabetic, central nervous system, estrogenic activities, and others. The present chapter aimed to comprehensively review the research advances on irisflorentin based on available literatures collected from different authentic scientific databases including Scifinder, Elsevier, and Pubmed. From another perspective, this review also had the purpose to discover the limitations of current researches on irisflorentin, such as the blank research area in the pharmacology in animals, toxicology, and clinical trial, which would provide new research perspectives for the future studies on this compound. Combining the advantages and limitations of existing researches on irisflorentin, we expect that the future research could allow this molecule to be used in clinical and health food.

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Authors and Affiliations

  1. CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China

    Ye Liu & Ming-quan Guo

  2. Cixi Institute of Biomedical Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, China

    Ming-quan Guo

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  1. Ye Liu
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  2. Ming-quan Guo
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Correspondence to Ming-quan Guo .

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Editors and Affiliations

  1. Department of Analytical Chemistry and Food Science, Universidade de Vigo, Vigo, Spain

    Jianbo Xiao

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Liu, Y., Guo, Mq. (2023). Irisflorentin: Advances on Resources, Metabolism, and Pharmacological Activities. In: Xiao, J. (eds) Handbook of Dietary Flavonoids. Springer, Cham. https://doi.org/10.1007/978-3-030-94753-8_99-1

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  • DOI: https://doi.org/10.1007/978-3-030-94753-8_99-1

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  • Print ISBN: 978-3-030-94753-8

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