Abstract
Multiple noncovalent forces do play a role in the binding between a protein antigen and an antibody directed against that protein. An antigen is bound by the antigen binding site of an antibody that consists of three hypervariable segments (complementarity determining regions, CDRs) of the light chain (L1, L2, L3) and three of the heavy chain (H1, H2, H3) (see Fig. 1).
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Welling, G.W., Welling-Wester, S. (2000). Mini-Antibody Affinity Chromatography of Lysozyme. In: Bailon, P., Ehrlich, G.K., Fung, WJ., Berthold, W. (eds) Affinity Chromatography. Methods in Molecular Biology, vol 147. Humana Press. https://doi.org/10.1007/978-1-60327-261-2_8
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DOI: https://doi.org/10.1007/978-1-60327-261-2_8
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