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Antibodies and Immunohistochemical Evaluation for the Diagnosis of Hematological Malignancies

An Overview

  • Protocol
Monoclonal Antibodies

Part of the book series: Methods in Molecular Biology ((MIMB,volume 378))

Abstract

The immunohistochemical evaluation of hematopoietic tissues has expanded our knowledge of both the function and pathological processes in a wide range of lymph nodal, extranodal tissues, and bone marrow. It is impossible to cover in detail the full range of immunohistochemical markers, which are available to study hematopoietic cells and their malignant counterparts. This chapter attempts to provide an overview of the antibodies, which are commonly used in studying the hematopoietic and lymphoid tissues and to diagnose hematological disorders. In addition, an immunohistology-based diagnostic approach to identify specific neoplastic entities is described in some length.

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Author information

Authors and Affiliations

  1. Department of Pathology, Indiana School of Medicine, Indianapolis, IN

    Dennis P. O’Malley (Laboratory Director)

  2. Immunohistochemistry Laboratory, Indianapolis, IN

    Dennis P. O’Malley (Laboratory Director)

  3. Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN

    Attilio Orazi

Authors
  1. Dennis P. O’Malley
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  2. Attilio Orazi
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Editor information

Editors and Affiliations

  1. Department of Hematopathology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA

    Maher Albitar

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© 2007 Humana Press Inc., Totowa, NJ

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O’Malley, D.P., Orazi, A. (2007). Antibodies and Immunohistochemical Evaluation for the Diagnosis of Hematological Malignancies. In: Albitar, M. (eds) Monoclonal Antibodies. Methods in Molecular Biology, vol 378. Humana Press. https://doi.org/10.1007/978-1-59745-323-3_8

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  • DOI: https://doi.org/10.1007/978-1-59745-323-3_8

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-567-5

  • Online ISBN: 978-1-59745-323-3

  • eBook Packages: Springer Protocols

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