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GLUT2-Expressing Neurons as Glucose Sensors in the Brain: Electrophysiological Analysis

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Glucose Transport

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1713))

Abstract

Brain glucose sensing plays an essential role in the regulation of energy homeostasis. Recent publications report that neurons expressing glucose transporter GLUT2 act as glucose sensors in different regions of the brain and contribute to the control of glucose homeostasis and feeding behavior. In this chapter we describe the methods used to explore glucose sensing in genetically tagged GLUT2-expressing neurons with slice electrophysiology.

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Author information

Authors and Affiliations

  1. Center for Integrative Genomics, University of Lausanne, Genopode Building, Lausanne, 1015, Switzerland

    Gwenaël Labouèbe & Bernard Thorens

  2. Department of Medicine, University of Fribourg, Fribourg, 1700, Switzerland

    Christophe Lamy

Authors
  1. Gwenaël Labouèbe
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  2. Bernard Thorens
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  3. Christophe Lamy
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Corresponding author

Correspondence to Gwenaël Labouèbe .

Editor information

Editors and Affiliations

  1. Department of Experimental Medical Science, Lund University, Lund, Sweden

    Karin Lindkvist-Petersson

  2. Department of Experimental Medical Science, Lund University, Lund, Sweden

    Jesper S Hansen

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Labouèbe, G., Thorens, B., Lamy, C. (2018). GLUT2-Expressing Neurons as Glucose Sensors in the Brain: Electrophysiological Analysis. In: Lindkvist-Petersson, K., Hansen, J. (eds) Glucose Transport. Methods in Molecular Biology, vol 1713. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7507-5_19

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  • DOI: https://doi.org/10.1007/978-1-4939-7507-5_19

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7506-8

  • Online ISBN: 978-1-4939-7507-5

  • eBook Packages: Springer Protocols

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