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Role of Exosomal MicroRNAs in Cell-to-Cell Communication

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miRNomics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2257))

Abstract

Exosomes, a type of extracellular vesicle, are small vesicles (30–100 nm) secreted into extracellular space from almost all types of cells. Exosomes mediate cell-to-cell communication carrying various biologically active molecules including microRNAs. Studies have shown that exosomal microRNAs play fundamental roles in healthy and pathological conditions such as immunity, cancer, and inflammation. In this chapter, we introduce the current knowledge on exosome biogenesis, techniques used in exosome research, and exosomal miRNA and their functions in biological and pathological processes.

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Authors and Affiliations

  1. Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Turkey

    Bora Tastan & Emre Tarakcioglu

  2. Department of Molecular Biology and Genetics, Science Faculty, Koç University, Istanbul, Turkey

    Yelda Birinci & Yongsoo Park

  3. Department of Neuroscience, Institute of Health Science, University of Dokuz Eylul, Izmir, Turkey

    Sermin Genc

  4. Izmir Biomedicine and Genome Center, Izmir, Turkey

    Sermin Genc

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  1. Bora Tastan
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  2. Emre Tarakcioglu
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  3. Yelda Birinci
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  4. Yongsoo Park
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  5. Sermin Genc
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Correspondence to Sermin Genc .

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Editors and Affiliations

  1. Medical Informatics and Bioinformatics, Institute for Measurement Engineering and Sensor Technology, Hochschule Ruhr West, University of Applied Sciences, Mülheim adR, Germany

    Jens Allmer

  2. Department of Information System, Galilee Digital Health Research Center (GDH), Zefat Academic College, Zefat, Israel

    Malik Yousef

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Tastan, B., Tarakcioglu, E., Birinci, Y., Park, Y., Genc, S. (2022). Role of Exosomal MicroRNAs in Cell-to-Cell Communication. In: Allmer, J., Yousef, M. (eds) miRNomics. Methods in Molecular Biology, vol 2257. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1170-8_14

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  • DOI: https://doi.org/10.1007/978-1-0716-1170-8_14

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