Abstract
The Open PHACTS Discovery Platform integrates several public databases, which can be of interest when annotating the results of a phenotypic screening campaign. Workflow tools provide easy-to-customize possibilities to access the platform. Here, we describe how to create such workflows for two different workflow tools (KNIME and Pipeline Pilot), including a protocol to annotate compounds (e.g., phenotypic screening hits) with compound classification, known protein targets, and classifications of the targets.
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References
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Acknowledgment
We wish to acknowledge the Open PHACTS Foundation (http://www.openphactsfoundation.org/), the charitable organization responsible for the Open PHACTS Discovery Platform, without which this work would not have been possible.
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Digles, D., Caracoti, A., Jacoby, E. (2018). Accessing the Open PHACTS Discovery Platform with Workflow Tools. In: Wagner, B. (eds) Phenotypic Screening. Methods in Molecular Biology, vol 1787. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7847-2_14
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DOI: https://doi.org/10.1007/978-1-4939-7847-2_14
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Online ISBN: 978-1-4939-7847-2
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