Skip to main content

Plant Pathway Databases

  • Protocol
Plant Bioinformatics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1374))

Abstract

Pathway databases provide information about the role of chemicals, genes, and gene products in the form of protein or RNA, their interactions leading to the formulation of metabolic, transport, regulatory, and signaling reactions. The reactions can then be tethered by the principle of inputs and outputs of one or more reaction to create pathways. This chapter provides a list of various online databases that carry information about plant pathways and provides a brief overview of how to use the pathway databases such as WikiPathways Plants Portal, MapMan and the cereal crop pathway databases like RiceCyc and MaizeCyc, that were developed using the Pathway Tools software.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Protocol
USD 49.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Dharmawardhana P, Ren L, Amarasinghe V, Monaco M, Thomason J, Ravenscroft D, McCouch S, Ware D, Jaiswal P (2013) A genome scale metabolic network for rice and accompanying analysis of tryptophan, auxin and serotonin biosynthesis regulation under biotic stress. Rice (N Y) 6(1):15

    Google Scholar 

  2. Monaco M, Sen TZ, Dharmawardhana P, Ren L, Schaeffer M, Naithani S, Amarasinghe V, Thomason J, Harper L, Gardiner J, Cannon E, Lawrence C, Ware D, Jaiswal P (2013) Maize metabolic network construction and transcriptome analysis. Plant Genome 6:1–12

    Article  Google Scholar 

  3. Usadel B, Poree F, Nagel A, Lohse M, Czedik-Eysenberg A, Stitt M (2009) A guide to using MapMan to visualize and compare Omics data in plants: a case study in the crop species, Maize. Plant Cell Environ 32(9):1211–1229

    Article  PubMed  Google Scholar 

  4. Hanumappa M, Preece J, Elser J, Nemeth D, Bono G, Wu K, Jaiswal P (2013) WikiPathways for plants: a community pathway curation portal and a case study in rice and Arabidopsis seed development networks. Rice (N Y) 6(1):14

    Google Scholar 

  5. Kelder T, van Iersel MP, Hanspers K, Kutmon M, Conklin BR, Evelo CT, Pico AR (2011) WikiPathways: building research communities on biological pathways. Nucleic Acids Res 40(Database issue):D1301–D1307

    PubMed Central  PubMed  Google Scholar 

  6. Caspi R, Altman T, Billington R, Dreher K, Foerster H, Fulcher CA, Holland TA, Keseler IM, Kothari A, Kubo A, Krummenacker M, Latendresse M, Mueller LA, Ong Q, Paley S, Subhraveti P, Weaver DS, Weerasinghe D, Zhang P, Karp PD (2014) The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases. Nucleic Acids Res 42(Database issue):D459–D471

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  7. Thimm BO, Gibon Y, Nagel A, Meyer S, Kruger P, Selbig J, Muller LA, Rhee SY, Stitt M (2004) MAPMAN: a user-driven tool to display genomics data sets onto diagrams of metabolic pathways and other biological processes. Plant J 37(6):914–939

    Article  CAS  PubMed  Google Scholar 

  8. Lohse M, Nagel A, Herter T, May P, Schroda M, Zrenner R, Tohge T, Fernie AR, Stitt M, Usadel B (2014) Mercator: a fast and simple web server for genome scale functional annotation of plant sequence data. Plant Cell Environ 37(5):1250–1258

    Article  CAS  PubMed  Google Scholar 

  9. Usadel B, Nagel A, Steinhauser D, Gibon Y, Blasing OE, Redestig H, Sreenivasulu N, Krall L, Hannah MA, Poree F, Fernie AR, Stitt M (2006) PageMan: an interactive ontology tool to generate, display, and annotate overview graphs for profiling experiments. BMC Bioinform 7:535

    Article  Google Scholar 

  10. van Iersel MP, Kelder T, Pico AR, Hanspers K, Coort S, Conklin BR, Evelo C (2008) Presenting and exploring biological pathways with PathVisio. BMC Bioinform 9:399

    Article  Google Scholar 

  11. Doniger SW, Salomonis N, Dahlquist KD, Vranizan K, Lawlor SC, Conklin BR (2003) MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol 4(1):6

    Article  Google Scholar 

  12. Gao J, Zhang C, van Iersel M, Zhang L, Xu D, Schultz N, Pico RA (2014) BridgeDb app: unifying identifier mapping services for Cytoscape. F1000Res 3:148

    PubMed Central  PubMed  Google Scholar 

  13. van Iersel MP, Pico AR, Kelder T, Gao J, Ho I, Hanspers K, Conklin BR, Evelo CT (2010) The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services. BMC Bioinform 11:5

    Article  Google Scholar 

  14. Jaiswal P (2011) Gramene database: a hub for comparative plant genomics. Methods Mol Biol 678:247–275

    Article  CAS  PubMed  Google Scholar 

  15. Jaiswal P, Ni J, Yap I, Ware D, Spooner W, Youens-Clark K, Ren L, Liang C, Hurwitz B, Zhao W, Ratnapu K, Faga B, Canaran P, Fogleman M, Hebbard C, Avraham S, Schmidt S, Casstevens TM, Buckler ES, Stein L, McCouch S (2006) Gramene: a genomics and genetics resource for rice. Rice Genet Newslett 22(1):9–16

    Google Scholar 

  16. Urbanczyk-Wochniak E, Sumner LW (2007) MedicCyc: a biochemical pathway database for Medicago truncatula. Bioinformatics 23(11):1418–1423

    Article  CAS  PubMed  Google Scholar 

  17. Zhang P, Dreher K, Karthikeyan A, Chi A, Pujar A, Caspi R, Karp P, Kirkup V, Latendresse M, Lee C, Mueller LA, Muller R, Rhee SY (2010) Creation of a genome-wide metabolic pathway database for Populus trichocarpa using a new approach for reconstruction and curation of metabolic pathways for plants. Plant Physiol 153(4):1479–1491

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  18. Nakao M, Bono H, Kawashima S, Kamiya T, Sato K, Goto S, Kanehisa M (1999) Genome-scale gene expression analysis and pathway reconstruction in KEGG. Genome Inform Ser Workshop Genome Inform 10:94–103

    CAS  PubMed  Google Scholar 

  19. Ogata H, Goto S, Fujibuchi W, Kanehisa M (1998) Computation with the KEGG pathway database. Biosystems 47(1-2):119–128

    Article  CAS  PubMed  Google Scholar 

  20. Monaco MK, Stein J, Naithani S, Wei S, Dharmawardhana P, Kumari S, Amarasinghe V, Youens-Clark K, Thomason J, Preece J, Pasternak S, Olson A, Jiao Y, Lu Z, Bolser D, Kerhornou A, Staines D, Walts B, Wu G, D’Eustachio P, Haw R, Croft D, Kersey PJ, Stein L, Jaiswal P, Ware D (2014) Gramene 2013: comparative plant genomics resources. Nucleic Acids Res 42(Database issue):D1193–D1199

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  21. Ling MH, Rabara RC, Tripathi P, Rushton PJ, Ge SX (2013) Extending MapMan ontology to tobacco for visualization of gene expression. Dataset Pap Biol 2013:pii: 706465

    Google Scholar 

  22. Toufighi K, Brady SM, Austin R, Ly E, Provart NJ (2005) The Botany Array Resource: e-Northerns, Expression Angling, and promoter analyses. Plant J 43(1):153–163

    Article  CAS  PubMed  Google Scholar 

  23. Orchard S, Ammari M, Aranda B, Breuza L, Briganti L, Broackes-Carter F, Campbell NH, Chavali G, Chen C, del-Toro N, Duesbury M, Dumousseau M, Galeota E, Hinz U, Iannuccelli M, Jagannathan S, Jimenez R, Khadake J, Lagreid A, Licata L, Lovering RC, Meldal B, Melidoni AN, Milagros M, Peluso D, Perfetto L, Porras P, Raghunath A, Ricard-Blum S, Roechert B, Stutz A, Tognolli M, van Roey K, Cesareni G, Hermjakob H (2014) The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases. Nucleic Acids Res 42(Database issue):D358–D363

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  24. Isserlin R, El-Badrawi RA, Bader GD (2011) The biomolecular interaction network database in PSI-MI 2.5. Database (Oxford) 2011:baq037

    Article  Google Scholar 

Download references

Acknowledgement

We kindly acknowledge current and former members of our respective laboratories and collaborative projects for their contribution to building pathway resources for the plant biology community. We also acknowledge the iPlant Collaborative (http://www.iplantcollaborative.org/) for hosting the Gramene’s PGDB pathway databases (http://pathway.iplantcollaborative.org/). We extend special thanks to numerous collaborators and domain experts who continue to contribute to the development and annotation of pathway databases. PJ acknowledges funding support by the US National Science Foundation (NSF) award IOS #1127112 and the funds made available by the Oregon State University. BU acknowledges funding support for the PlabiPD project FKZ 0315961

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Pankaj Jaiswal .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer Science+Business Media New York

About this protocol

Cite this protocol

Jaiswal, P., Usadel, B. (2016). Plant Pathway Databases. In: Edwards, D. (eds) Plant Bioinformatics. Methods in Molecular Biology, vol 1374. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3167-5_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-3167-5_4

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3166-8

  • Online ISBN: 978-1-4939-3167-5

  • eBook Packages: Springer Protocols

Publish with us

Policies and ethics