Phytochemicals and biological activities of species from the genus Maytenus Lei ZhangMing-Yue JiMin-Hui Li Review Article 18 February 2020 Pages: 575 - 606
Repression of the transcriptional activity of ERRα with sequence-specific DNA-binding polyamides Chien-yu ChenYang LiBangyan L. Stiles Original Research 26 February 2020 Pages: 607 - 616
In vitro anticancer activity of pyrano[3, 2-c]chromene derivatives with both cell cycle arrest and apoptosis induction Ahmed M. El-AgrodyAhmed M. FoudaMohammad Y. Alfaifi Original Research 08 February 2020 Pages: 617 - 629
Synthesis and anticancer activities of thiosemicarbazones derivatives of thiochromanones and related scaffolds Jiangli SongRongkai PanShenggui Liu Original Research 05 February 2020 Pages: 630 - 642
Synthesis of novel dimeric compounds containing triazole using click method and their selective antiproliferative and proapoptotic potential via mitochondrial apoptosis signaling H. R. Ferhat KarabulutAli Osman KaratavukZeynep Banu Doğanlar Original Research 23 January 2020 Pages: 643 - 655
Antioxidant and anti-inflammatory cembrane-type diterpenoid from Echinoidea sea urchin Stomopneustes variolaris attenuates pro-inflammatory 5-lipoxygenase Prima FrancisKajal Chakraborty Original Research 27 January 2020 Pages: 656 - 664
In vitro and in silico evaluations of new aryloxy-1,4-naphthoquinones as anti-Trypanosoma cruzi agents Alejandra GonzálezNohemí BecerraKarina Vázquez Original Research 25 January 2020 Pages: 665 - 674
Synthesis and anticancer activity of new tetrahydroquinoline hybrid derivatives tethered to isoxazoline moiety Cristian C. BernalLuis C. VesgaArnold R. Romero Bohórquez Original Research 27 January 2020 Pages: 675 - 689
Exploration of the selective binding mechanism of GSK3β via molecular modeling and molecular dynamics simulation studies Linkai MouZilong MaXiangyu Chen Original Research 27 January 2020 Pages: 690 - 698
Microwave-assisted synthesis and in vitro antiproliferative activity of some novel 1,2,3-triazole-based pyrazole aldehydes and their benzimidazole derivatives Dongamanti AshokM. Ram ReddyM. Sarasija Original Research 31 January 2020 Pages: 699 - 706
Anticoagulant activity screening of an in-house database of natural compounds for discovering novel selective factor Xa inhibitors; a combined in silico and in vitro approach Reham S. IbrahimRahma SR. MahrousRasha M. Abu EL-Khair Original Research 20 February 2020 Pages: 707 - 726
Pharmacophore modeling, atom-based 3D-QSAR and molecular docking studies on N-benzylpyrimidin-4-amine derivatives as VCP/p97 inhibitors Chenxi GuYonglei ZhangYongqiang Zhu Original Research 22 February 2020 Pages: 727 - 737
Synthesis and analgesic activity of aliphatic ketones-derived chiral hexahydro-2H-chromenes Irina Il’inaEkaterina MorozovaNariman Salakhutdinov Original Research 07 February 2020 Pages: 738 - 747
Green synthesis, antitubercular evaluation, and molecular docking studies of ethyl 3,5-dicyano-6-oxo-2,4-diarylpiperidine-3-carboxylate derivatives Thuraka SekharPinnu ThriveniUday Sankar Allam Original Research 26 February 2020 Pages: 748 - 758
A new pimarane-type diterpene obtained by biotransformation inhibits human HCT-116 colorectal carcinoma through inhibition of LTA4H activity Amira MiraMohamed A. SabryFatma M. Abdel Bar Original Research 11 February 2020 Pages: 759 - 766
Synthesis and biological evaluation of fluorescent GAT-ligands based on asymmetric substituted BODIPY dyes Markus DaerrLars AllmendingerKlaus T. Wanner Original Research 15 February 2020 Pages: 767 - 782
Anticonvulsant activity of new 3- and 4-benzoilpiridines oxime derivatives in comparison with valproic acid Igor Olegovich GaydukovTatyana Aleksandrovna VoroninaInga Sergeevna Kutepova Original Research 22 February 2020 Pages: 783 - 792
Systematic understanding of the potential targets and pharmacological mechanisms of acteoside by network pharmacology approach Yiliyasi AisaKurexi YunusiNa Mi Original Research 25 February 2020 Pages: 793 - 801
Targeted selective degradation of Bruton’s tyrosine kinase by PROTACs Shaodong LiuYang DaJun Lin Original Research 28 February 2020 Pages: 802 - 808