1. Mechanistic studies of the apoptosis induced by the macrocyclic natural product tetrandrine in MGC 803 cells

   • Sai-Qi Wang
   • Hong-Lin Hou
   • Xiao-Bing Chen

   Original Research 08 December 2018 Pages: 107 - 115

   

2. Oxymatrine improves L-arginine-induced acute pancreatitis related intestinal injury via regulating AKT/NFkB and claudins signaling

   • Hui Zang
   • Zhiqiang Zhang
   • Bensong Gong

   Original Research 05 December 2018 Pages: 116 - 124

   

3. Identification of protein arginine methyltransferase 7 (PRMT7) inhibitor by virtual screening and biological evaluation in vitro

   • Linlin Liu
   • Xiaoning Kai
   • Jian Gao

   Original Research 19 December 2018 Pages: 125 - 132

   

4. Novel anti-cancer agents: design, synthesis, biological activity, molecular docking, and MD simulations of 2, 3, 4, 5-tetrahydro-1H-pyrido-[4,3-b]indole derivatives

   • Yu Feng
   • Xingxing Teng
   • Lianbao Ye

   Original Research 14 December 2018 Pages: 133 - 142

   

5. Comparative α-glucosidase and α-amylase inhibition studies of rhodanine–pyrazole conjugates and their simple rhodanine analogues

   • Parvesh Singh
   • Serisha Mothilal
   • Md. Shahidul Islam

   Original Research 13 December 2018 Pages: 143 - 159

   

6. Controlled release of losartan from acid- and heat-treated halloysite nanotubes

   • Farid Moeinpour
   • Faezeh Soofivand
   • Fatemeh S. Mohseni-Shahri

   Original Research 12 December 2018 Pages: 160 - 168

   

7. Green synthesis, antileishmanial activity evaluation, and in silico studies of new amino acid-coupled 1,2,4-triazoles

   • Ahmed M. El-Saghier
   • Mounier A. Mohamed
   • Adnan A. Bekhit

   Original Research 22 December 2018 Pages: 169 - 181

   

8. The discovery of purine-based agents targeting triple-negative breast cancer and the αB-crystallin/VEGF protein–protein interaction

   • Nelly A. Fosu-Mensah
   • Wen Jiang
   • Andrew D. Westwell

   Original Research Open access 21 December 2018 Pages: 182 - 202

   

9. Design, synthesis, antiproliferative and antibacterial evaluation of quinazolinone derivatives

   • Hai-Xin Wang
   • Hai-Ying Liu
   • Bao-Quan Chen

   Original Research 26 December 2018 Pages: 203 - 214

   

10. Syntheses and in silico pharmacokinetic predictions of glycosylhydrazinyl-pyrazolo[1,5-c]pyrimidines and pyrazolo[1,5-c]triazolo[4,3-a]pyrimidines as anti-proliferative agents

    • Kamal F. M. Atta
    • Omaima O. M. Farahat
    • El Sayed H. El Ashry

    Original Research 17 December 2018 Pages: 215 - 227