1. Design, synthesis and biological evaluation of (E)-3-(3,4,5-trimethoxyphenyl) acrylic acid (TMCA) amide derivatives as anticonvulsant and sedative agents

   • Zefeng Zhao
   • Yajun Bai
   • Xiaohui Zheng

   Original Research 15 September 2018 Pages: 2387 - 2396

   

2. Synthesis, cytotoxic activity, and mode of action of new Santacruzamate A analogs

   • Silmara N. Andrade
   • Fernanda C. G. Evangelista
   • Fernando P. Varotti

   Original Research 14 September 2018 Pages: 2397 - 2413

   

3. Synthesis of chalcones with antiproliferative activity on the SH-SY5Y neuroblastoma cell line: Quantitative Structure–Activity Relationship Models

   • Marco Mellado
   • Alejandro Madrid
   • Mauricio Cuellar

   Original Research 15 September 2018 Pages: 2414 - 2425

   

4. Synthesis and evaluation of cadiolide analogues as inhibitors of bacterial biofilm formation

   • Simone Z. Mairink
   • Luiz C. A. Barbosa
   • Luiz M. Farias

   Original Research 17 September 2018 Pages: 2426 - 2436

   

5. Design and synthesis of novel triazolo-lapatinib hybrids as inhibitors of breast cancer cells

   • YeHui Shi
   • Wei Zhang
   • CuiGai Bai

   Original Research 01 November 2018 Pages: 2437 - 2445

   

6. An unreported polyether macrocyclic lactone with antioxidative and anti-lipoxygenase activities from the Babylonidae gastropod mollusc Babylonia spirata

   • Soumya Salas
   • Kajal Chakraborty

   Original Research 24 September 2018 Pages: 2446 - 2453

   

7. Synthesis and trypanocide activity of chloro-l-tyrosine and bromo-l-tyrosine derivatives

   • Manuel Pastrana Restrepo
   • Elkin Galeano Jaramillo
   • Sara Robledo Restrepo

   Original Research 25 September 2018 Pages: 2454 - 2465

   

8. QSAR studies of new pyrido[3,4-b]indole derivatives as inhibitors of colon and pancreatic cancer cell proliferation

   • Hemantkumar Deokar
   • Mrunalini Deokar
   • John K. Buolamwini

   Original Research 03 October 2018 Pages: 2466 - 2481

   

9. Diazabenzo[a]phenoxazone sulphonamides: synthesis, in-silico and in-vitro antimicrobial studies

   • Mercy A. Ezeokonkwo
   • Cosmas C. Eze
   • Fidelia N. Ibeanu

   Original Research 10 October 2018 Pages: 2482 - 2493

   

10. Uses of dimedone for the synthesis of thiazole derivatives as new anti-tumor, c-Met, tyrosine kinase, and Pim-1 inhibitions

    • Rafat M. Mohareb
    • Thomas M. Klapötke
    • Elena Reinhardt

    Original Research 20 October 2018 Pages: 2494 - 2511

    

11. Synthesis, antitrypanosomal activity and molecular docking studies of pyrimidine derivatives

    • Sebastião José de Melo
    • Zenaide Severina do Monte
    • Valeria Rêgo Alves Pereira

    Original Research 26 October 2018 Pages: 2512 - 2522

    

12. Antioxidant properties of Calendula officinalis L. (Asteraceae) on Fe²⁺-initiated peroxidation of rat brain mitochondria

    • P. A. Zeinsteger
    • J. L. Barberón
    • A. Palacios

    Original Research 26 October 2018 Pages: 2523 - 2529

    

13. Synthesis and spectroscopic analysis of benzylidene imidazolone linked to P-porphyrins through axial ligand

    • Jin Matsumoto
    • Kyosuke Takemori
    • Masahide Yasuda

    Original Research 27 October 2018 Pages: 2530 - 2537

    

14. Synthesis and antiviral study of novel 4-(2-(6-amino-4-oxo-4,5-dihydro-1H-pyrrolo[2,3-d]pyrimidin-3-yl)ethyl)benzamide derivatives

    • Selvakumar Balaraman
    • Nagaraj Nayak
    • Kuppanagounder P. Elango

    Original Research 27 October 2018 Pages: 2538 - 2546