1. The critical region on the human Xq

   • Eeva Therman
   • Renata Laxova
   • Barbara Susman

   Review Article Pages: 455 - 461

2. Variability in expression of common fragile sites: in search of a new criterion

   • Diane K. Jordan
   • Trudy L. Burns
   • Shivanand R. Patil

   Original Investigations Pages: 462 - 466

3. TaqI HLA-B and -DRB RFLP analysis can predict disease in siblings of affected children with 21-hydroxylase deficiency

   • Olle Olerup
   • Holger Luthman
   • Barbro Haglund-Stengler

   Original Investigations Pages: 467 - 472

4. The gene for 17beta-hydroxysteroid dehydrogenase maps to human chromosome 17, bands q12–q21, and shows an RFLP with ScaI

   • Robert Winqvist
   • Hellevi Peltoketo
   • Reijo Vihko

   Original Investigations Pages: 473 - 476

5. Leukaemia and transient leukaemia in Down syndrome

   • Lennart Iselius
   • Patricia Jacobs
   • Newton Morton

   Original Investigations Pages: 477 - 485

6. Y isochromosome associated with a mosaic karyotype and inactivation of the centromere

   • Thomas Haaf
   • Michael Schmid

   Original Investigations Pages: 486 - 490

7. Deletion of specific sequences or modification of centromeric chromatin are responsible for Y chromosome centromere inactivation

   • Paola Maraschio
   • Orsetta Zuffardi
   • Rossella Tupler

   Original Investigations Pages: 491 - 494

8. Significance of structural chromosome aberrations in human sperm: analysis of induced aberrations

   • A. Genescá
   • J. Benet
   • J. Egozcue

   Original Investigations Pages: 495 - 499

9. Identification of a compound heterozygote for adenine phosphoribosyltransferase deficiency (APRT^*J/APRT^*Q0) leading to 2,8-dihydroxyadenine urolithiasis

   • Naoyuki Kamatani
   • Shoko Kuroshima
   • Masayuki Hakoda

   Original Investigations Pages: 500 - 504

10. β-Galactosidase-deficient human fibroblasts: uptake and processing of the exogenous precursor enzyme expressed by stable transformant COS cells

    • Akihiro Oshima
    • Kohji Itoh
    • Yoshiyuki Suzuki

    Original Investigations Pages: 505 - 508

11. Locus assignment of human α-globin structural mutants by selective enzymatic amplification of α1 and α2-globin cDNAs

    • Avgi Mamalaki
    • Margrit Horanyi
    • Nicholas K. Moschonas

    Original Investigations Pages: 509 - 512

12. Involvement of the region 13q14 in a patient with adamantinoma of the long bones

    • Gabriella Sozzi
    • Monica Miozzo
    • Giuseppe Della Porta

    Original Investigations Pages: 513 - 515

13. Investigation of three patients with the “ring syndrome”, including familial transmission of ring 5, and estimation of reproductive risks

    • K. D. MacDermot
    • E. Jack
    • M. d'A. Crawfurd

    Original Investigations Pages: 516 - 520

14. The origin of sickle cell alleles in Israel

    • Deborah Rund
    • Naomi Kornhendler
    • Ariella Oppenheim

    Original Investigations Pages: 521 - 524

15. Amplification of the COL2A1 3′ variable region used for segregation analysis in a family with the Stickler syndrome

    • Linda Priestley
    • D. Kumar
    • Bryan Sykes

    Original Investigations Pages: 525 - 526

16. The human QARS locus: assignment of the human gene for glutaminyl-tRNA synthetase to chromosome 1q32–42

    • N. Kunze
    • E. Bittler
    • R. Knippers

    Original Investigations Pages: 527 - 530

17. Molecular analysis of the human MHC class I region in hereditary haemochromatosis

    • Deirdre K. Lord
    • I. Dunham
    • Timothy M. Cox

    Original Investigations Pages: 531 - 536

18. Molecular characterisation of two alpha-1-antitrypsin deficiency variants: proteinase inhibitor (Pi) Null_Newport (Gly¹¹⁵→Ser) and (Pi) Z Wrexham (Ser⁻¹⁹→Leu)

    • Alexander Graham
    • Noor A. Kalsheker
    • Alexander F. Markham

    Original Investigations Pages: 537 - 540

19. Linkage disequilibrium detected between dystrophia myotonica and APOC2 locus in the Finnish population

    • Pekka Nokelainen
    • Leena Alanen-Kurki
    • Leena Peltonen

    Original Investigations Pages: 541 - 545

20. Chromosomal aberrations in patients with primary biliary cirrhosis

    • Arman Notghi
    • Ursula Nestle
    • Christian Rittner

    Original Investigations Pages: 546 - 550

21. In situ chromosome preparation technique for simultaneous cytogenetic and immunocytochemical studies on cell cultures of solid tumors

    • Wolfram Henn
    • Jutta Lehr
    • Klaus D. Zang

    Short Communications Pages: 551 - 554

22. Rapid diagnosis of Miller-Dieker syndrome and isolated lissencephaly sequence by the polymerase chain reaction

    • Jacqueline R. Batanian
    • Susan A. Ledbetter
    • David H. Ledbetter

    Short Communications Pages: 555 - 559

23. Close linkage of the Wilsons's disease locus to D13S12 in the chromosomal region 13q21 and not to ESD in 13q14

    • Roderick H. J. Houwen
    • Hans Scheffer
    • Charles H. C. M. Buys

    Short Communications Pages: 560 - 562

24. Deletion 3q27→3qter associated with a new skin disorder?

    • Rudolf Happle

    Letters to the Editors Pages: 563 - 564