1. Unintended CRISPR-Cas9 editing outcomes: a review of the detection and prevalence of structural variants generated by gene-editing in human cells

   • John Murray Topp Hunt
   • Christopher Allan Samson
   • Hilary M. Sheppard

   Review Open access 24 April 2023 Pages: 705 - 720

   

2. SNV/indel hypermutator phenotype in biallelic RAD51C variant: Fanconi anemia

   • Roni Zemet
   • Haowei Du
   • Paweł Stankiewicz

   Original Investigation 09 April 2023 Pages: 721 - 733

   

3. ADGB variants cause asthenozoospermia and male infertility

   • Ronggui Qu
   • Zhihua Zhang
   • Yanping Kuang

   Original Investigation 30 March 2023 Pages: 735 - 748

   

4. Predicting ExWAS findings from GWAS data: a shorter path to causal genes

   • Kevin Y. H. Liang
   • Yossi Farjoun
   • J. Brent Richards

   Original Investigation 02 April 2023 Pages: 749 - 758

   

5. Clinical and genome-wide association analysis of chemoradiation-induced hearing loss in nasopharyngeal carcinoma

   • Yong-Qiao He
   • Lu-Ting Luo
   • Wei-Hua Jia

   Original Investigation Open access 16 April 2023 Pages: 759 - 772

   

6. High diagnostic potential of short and long read genome sequencing with transcriptome analysis in exome-negative developmental disorders

   • François Lecoquierre
   • Olivier Quenez
   • Gaël Nicolas

   Original Investigation 19 April 2023 Pages: 773 - 783

   

7. Specifications and validation of the ACMG/AMP criteria for clinical interpretation of sequence variants in collagen genes associated with joint hypermobility

   • Maria Pia Leone
   • Silvia Morlino
   • Marco Castori

   Original Investigation 20 April 2023 Pages: 785 - 808

   

8. Proteome-wide Mendelian randomization reveals the causal effects of immune-related plasma proteins on psychiatric disorders

   • Xinglun Dang
   • Meng Song
   • Xiong-Jian Luo

   Original Investigation 21 April 2023 Pages: 809 - 818

   

9. Assessing variants of uncertain significance implicated in hearing loss using a comprehensive deafness proteome

   • Mallory R. Tollefson
   • Rose A. Gogal
   • Michael J. Schnieders

   Original Investigation Open access 22 April 2023 Pages: 819 - 834

   

10. Prenatal diagnosis in the fetal hyperechogenic kidneys: assessment using chromosomal microarray analysis and exome sequencing

    • Ruibin Huang
    • Fang Fu
    • Can Liao

    Original Investigation 24 April 2023 Pages: 835 - 847