Considerations in the Design and Analysis of Postoperative Dental Pain Studies David A. EdelmanLeland D. Loose OriginalPaper 31 December 2002 Pages: 481 - 485
Computable Protocol Models for Interactive Trial Design Michael G. Kahn OriginalPaper 31 December 2002 Pages: 487 - 497
What Type of Pivotal Study Design is Appropriate for an Investigational New Drug to Manage Chronic Angle Closure Glaucoma: Active Control or Placebo? Yeong-Liang LinBey-Liing MauMong-Ling Chu OriginalPaper 31 December 2002 Pages: 499 - 500
A Standardized Composite Clinical Score for Inhaled Corticosteroids Taper Studies in Asthma Sumiko ShingoJi ZhangJonathan A. Leff OriginalPaper 31 December 2002 Pages: 501 - 508
The Challenges of Nonpharmacological Trials: Blinding and Other Issues Using Acupuncture Research as an Example Kien Vinh Trinh OriginalPaper 31 December 2002 Pages: 509 - 511
Assessment of the Extrapolation of Foreign Clinical Data for Registration Purposes Yeong-Liang LinYi Jin ChiouMong-Ling Chu OriginalPaper 31 December 2002 Pages: 513 - 516
Report of a Workshop on Confirmatory Evidence to Support a Single Clinical Trial As a Basis for New Drug Approval Carl C. PeckJill Wechsler OriginalPaper 31 December 2002 Pages: 517 - 534
Research Methodology Evaluating Complementary and Alternative Therapies Carmen TamayoHeather BoonKien Trinh OriginalPaper 31 December 2002 Pages: 535 - 548
Recommendations to the Food and Drug Administration: Metered Dose Inhaler Tests and Methods in the Chemistry, Manufacturing, and Controls Draft Guidances for Metered Dose Inhalers and Dry Powder Inhalers Inhalation Technology Focus Group/International Pharmaceutical Aerosol Consortium on Regulation and Science Tests and Methods Technical TeamLee M. Nagao OriginalPaper 31 December 2002 Pages: 549 - 556
Component Scores, or Total Scores over Components? William H. ChangChristy Chuang-Stein OriginalPaper 31 December 2002 Pages: 557 - 564
A Set of Quality Criteria for Statistical Programming Allan Glaser OriginalPaper 31 December 2002 Pages: 565 - 570
On the Use of the Accelerated Failure Time Model As An Alternative to the Proportional Hazards Model in the Treatment of Time to Event Data: A Case Study in Influenza Richard KayNelson Kinnersley OriginalPaper 31 December 2002 Pages: 571 - 579
Phase 1 Oncology Clinical Trials for Related Subpopulations: The Power Walk Design Georgene SchroederJeff A. SloanCharles Erlichman OriginalPaper 31 December 2002 Pages: 581 - 593
Effects of Bias Adjustment on Actuarial Survival Curves Michael Ross ChernickErik PoulsenYong Wang OriginalPaper 31 December 2002 Pages: 595 - 609
The Theory of Constraints: A Unique Alternative to Traditional Project Management Eugene KaniaGayle HousdenKen Hitchner OriginalPaper 31 December 2002 Pages: 611 - 621
Focused Portfolio Measures to Support Decision Making Throughout the Pipeline Sue E. Steven OriginalPaper 31 December 2002 Pages: 623 - 630
Quality Control Issues Related to Biological Products: Microbial Contamination King C. LeeLeyla Toksoy OriginalPaper 31 December 2002 Pages: 631 - 634
Problems and Prospects for Good Manufacturing Practice for Herbal Drugs in Indian Systems of Medicine Pulok K. Mukherjee OriginalPaper 31 December 2002 Pages: 635 - 644
Current Status and Emerging Opportunities in Replacement of the Lifetime Mouse Cancer Bioassay Beatriz Silva-LimaJan Willem van der Laan OriginalPaper 31 December 2002 Pages: 645 - 657
Converting Legacy Data to MedDRA: Approach and Implications Thanh Van T. Doan OriginalPaper 31 December 2002 Pages: 659 - 666
Pharmacovigilance Licensing: the Role of Drug Safety in Product Transfers Martin Karl Friedrich Becker OriginalPaper 31 December 2002 Pages: 667 - 671
Strategies for Processing Drug Information Documents and Developing Drug Information Files Charles F. CurranMurali N. Sundar OriginalPaper 31 December 2002 Pages: 673 - 682
Controlling the Increased Complexity of Electronic Clinical data Collection and Management Technology by data Modeling and System Engineering Ülo Palm OriginalPaper 31 December 2002 Pages: 683 - 692
The Effects of Print Format in Direct-To-Consumer Prescription Drug Advertisements on Risk Knowledge and Preference Michael S. WogalterTonya L. Smith-JacksonCorrina S. Paine OriginalPaper 31 December 2002 Pages: 693 - 705
Leveraging the Internet to Deliver Dramatic Cost Efficiencies: Webcasting in Clinical Research Ellis Wilson Jr OriginalPaper 31 December 2002 Pages: 707 - 715
Centers for Education and Research on Therapeutics (CERTs) Judith M. KramerLynn A. BoscoRobert M. Califf OriginalPaper 31 December 2002 Pages: 717 - 723
