Novel pyrrolo[2,3-d]pyrimidine antifolate TNP-351: cytotoxic effect on methotrexate-resistant CCRF-CEM cells and inhibition of transformylases of de novo purine biosynthesis Fumio ItohOrsola RusselloG. Peter Beardsley Original Articles Pages: 273 - 279
The quinoline-3-carboxamide Linomide inhibits angiogenesis in vivo P. BorgströmI. P. Torres FilhoB. Hartley-Asp Original Articles Pages: 280 - 286
Antitumor effects of IST-622, a novel synthetic derivative of chartreusin, against murine and human tumor lines following oral administration Tazuko TashiroKenji KonShigeru Tsukagoshi Original Articles Pages: 287 - 292
Comparison of 5-fluorouracil anabolite levels after intravenous bolus and continuous infusion Theodore A. SteinBeverly BaileyGerard P. Burns Original Articles Pages: 293 - 296
Evaluation of methotrexate tissue exposure by in situ microdialysis in a rat model Per O. EkstrømAnders AndersenLars Slørdal Original Articles Pages: 297 - 301
Thermal enhancement of drug uptake and DNA adducts as a possible mechanism for the effect of sequencing hyperthermia on cisplatin-induced cytotoxicity in L1210 cells Shinji OhnoZahid H. SiddikJoan M. C. Bull Original Articles Pages: 302 - 306
Chemomodulation of drugs involved in multidrug resistance in chronic lymphatic leukemia of the B-cell type A. ReichleH. DiddensR. Andreesen Original Articles Pages: 307 - 316
Preclinical pharmacology of bizelesin, a potent bifunctional analog of the DNA-binding antibiotic CC-1065 Denise L. WalkerJoel M. ReidMatthew M. Ames Original Articles Pages: 317 - 322
Effects of intralesional injection of cisplatin dissolved in urografin and lipiodol on Ehrlich ascites tumor and normal tissues of CD-1 mice Jose E. LandritoKoji YoshigaKazuaki Takada Original Articles Pages: 323 - 330
Phase I study of high-dose cisplatin, ifosfamide, and etoposide Edith A. PerezPaul C. SowrayDavid R. Gandara Original Articles Pages: 331 - 334
Comparative effects of taxol and Taxotere on two different human carcinoma cell lines Patrick GarciaDiane BraguerClaudette Briand Original Articles Pages: 335 - 343
Increased intracellular Ca2+ signaling caused by the antitumor agent helenalin and its analogues Garth PowisAlfred GallegosRosanne Bonjouklian Original Articles Pages: 344 - 350
Growth kinetics of L1210 leukemic cells exposed to different concentration courses of methotrexate in vitro Stefan GimmelH. Rainer Maurer Original Articles Pages: 351 - 355
Bi-weekly vincristine, epirubicin and methylprednisolone in alkylator-refractory multiple myeloma Mark VincentGlen GossRobert Corringham Clinical Trial Report Pages: 356 - 360