Interleukin 33 supports squamous cell carcinoma growth via a dual effect on tumour proliferation, migration and invasion, and T cell activation Graziela PerriVanessa Garcia Vilas BoasAna Paula Campanelli Research Open access 25 April 2024 Article: 110
Synergistic immunomodulatory effect of synbiotics pre- and postoperative resection of pancreatic ductal adenocarcinoma: a randomized controlled study Sara MaherHesham A. ElmeligyManal Kamel Research Open access 25 April 2024 Article: 109
A2AR-mediated CXCL5 upregulation on macrophages promotes NSCLC progression via NETosis Qingyang LeiShanshan ZhenYi Zhang Research Open access 20 April 2024 Article: 108
A phase I trial of autologous RAK cell immunotherapy in metastatic renal cell carcinoma Jing XuWen ZhangJie Ma Research Open access 20 April 2024 Article: 107
Global real-world experiences with pembrolizumab in advanced urothelial carcinoma after platinum-based chemotherapy: the ARON-2 study Francesco MassariMatteo SantoniJoaquim Bellmunt Research Open access 18 April 2024 Article: 106
Correction to: Dominant‑negative transforming growth factor‑β receptor‑armoured mesothelin‑targeted chimeric antigen receptor T cells slow tumour growth in a mouse model of ovarian cancer Ke LiJing XuYu Kang Correction Open access 18 April 2024 Article: 105
Associations of granulocyte colony-stimulating factor with toxicities and efficacy of chimeric antigen receptor T-cell therapy in relapsed or refractory B-cell acute lymphoblastic leukemia Sha MaYing WangKailin Xu Research Open access 17 April 2024 Article: 104
Intratumor injection of BCG Ag85A high-affinity peptides enhanced anti-tumor efficacy in PPD-positive melanoma Lanqun QinGuiying ZhangZhengyun Zou Research Open access 17 April 2024 Article: 103
TLR5 agonist in combination with anti-PD-1 treatment enhances anti-tumor effect through M1/M2 macrophage polarization shift and CD8+ T cell priming Junseok LeeKeon-Il ImSeok-Goo Cho Research Open access 17 April 2024 Article: 102
Expansion of tumor-infiltrating lymphocytes from head and neck squamous cell carcinoma to assess the potential of adoptive cell therapy Sangjoon ChoiMofazzal HossainHee Jin Lee Research Open access 17 April 2024 Article: 101
Comparative performance of scFv-based anti-BCMA CAR formats for improved T cell therapy in multiple myeloma Sophia StockLuisa FertigSebastian Kobold Research Open access 17 April 2024 Article: 100
T-cell subsets and cytokines are indicative of neoadjuvant chemoimmunotherapy responses in NSCLC Ling YiZiwei XuYi Han Research Open access 15 April 2024 Article: 99
Incorporating IL7 receptor alpha signaling in the endodomain of B7H3-targeting chimeric antigen receptor T cells mediates antitumor activity in glioblastoma Nithidol SakunrangsitNattarika KhuisangeamSupannikar Tawinwung Research Open access 15 April 2024 Article: 98
Integrating bulk and single-cell sequencing data to construct a Scissor+ dendritic cells prognostic model for predicting prognosis and immune responses in ESCC Maosheng ChengJianqi XiongShuang Chen Research Open access 15 April 2024 Article: 97
CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival Jessica WedigShrina JasaniThomas A. Mace Research Open access 15 April 2024 Article: 96
Dual-loss of PBRM1 and RAD51 identifies hyper-sensitive subset patients to immunotherapy in clear cell renal cell carcinoma Ziyang XuWenbin JiangJiejie Xu Research Open access 12 April 2024 Article: 95
Bifidobacterium modulation of tumor immunotherapy and its mechanism Bo PeiShixuan PengFuxiang Zhou Review Open access 02 April 2024 Article: 94
The prognostic and potentially immunomodulatory role of cartilage oligomeric matrix protein in patients with gastric and esophageal adenocarcinoma Konstantinos S. PapadakosGilar Gorji-BahriAnna M. Blom Research Open access 02 April 2024 Article: 93
Activation of STING by the novel liposomal TLC388 enhances the therapeutic response to anti-PD-1 antibodies in combination with radiotherapy Jhen-Yu ChenPo-Yu LinKevin Chih-Yang Huang Research Open access 02 April 2024 Article: 92
circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis Qingtao LiuPei XuFangbao Ding Research Open access 30 March 2024 Article: 91
IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models Justin YuJacob GadwaSana D. Karam Research Open access 30 March 2024 Article: 90
Ezabenlimab (BI 754091), an anti-PD-1 antibody, in patients with advanced solid tumours Manish R. PatelMelissa JohnsonLillian L. Siu Research Open access 30 March 2024 Article: 89
Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression Jingbo MaJian TanKeqiang Liu Research Open access 30 March 2024 Article: 88
The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy Wenxin LuGuangyu WuLiwei Wang Research Open access 30 March 2024 Article: 87
SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue Kelly J. GregoryHolly MasonSallie S. Schneider Brief Report Open access 30 March 2024 Article: 86
TGF-β1 and TGF-βR1 variants are associated with clinical outcomes in smoking-related head and neck cancer patients treated with chemoradiation through modulating microRNA-mediated regulation Zihao NiuPeng SunGuojun Li Research Open access 30 March 2024 Article: 85
IL-2 promotes expansion and intratumoral accumulation of tumor infiltrating dendritic cells in pancreatic cancer Tingting GongXinyang HuangQi Wang Research Open access 30 March 2024 Article: 84
23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling Zeping FanYaru CuiWenbin Duan Research Open access 30 March 2024 Article: 83
DR30318, a novel tri-specific T cell engager for Claudin 18.2 positive cancers immunotherapy Zhe MaZhenxing ZhouLushan Yu Research Open access 30 March 2024 Article: 82
Characterization of a novel anti-PVRIG antibody with Fc-competent function that exerts strong antitumor effects via NK activation in preclinical models Hongyu XueZhimin ZhangKai Chen Research Open access 30 March 2024 Article: 81
Let-7i enhances anti-tumour immunity and suppresses ovarian tumour growth Andrew N. WilkinsonRui ChenSherry Y. Wu Research Open access 30 March 2024 Article: 80
Efficacy of immune checkpoint inhibitors differs in various status of carcinoma: a study based on 29 cohorts with 3255 participants Chunlan WuYujun KeXianhe Xie Research Open access 30 March 2024 Article: 79
Lipid droplets-related Perilipin-3: potential immune checkpoint and oncogene in oral squamous cell carcinoma Yijia HeLingyun LiuLiang Ding Research Open access 30 March 2024 Article: 78
Targeting osteosarcoma with canine B7-H3 CAR T cells and impact of CXCR2 Co-expression on functional activity Jennifer W. CaoJessica LakeSteven Dow Research Open access 30 March 2024 Article: 77
PGRN inhibits CD8+T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM Ting ZhouHusun QianBianqin Guo Research Open access 30 March 2024 Article: 76
Co-targeting CD47 and VEGF elicited potent anti-tumor effects in gastric cancer Kaiqi ZhangYuan XuKai Yin Research Open access 27 March 2024 Article: 75
Clinical evidence for efficacy of pembrolizumab in MSI-H and TMB-H advanced solid tumor: results from three cancer centers in China Huan YanLianxi SongLiang Zeng Research Open access 07 March 2024 Article: 74
Oct4 activates IL-17A to orchestrate M2 macrophage polarization and cervical cancer metastasis Zhuoqiong BianXiaoling WuYidong Wang Research Open access 02 March 2024 Article: 73
A phase 2 study of AZD4635 in combination with durvalumab or oleclumab in patients with metastatic castration-resistant prostate cancer Gerald S. FalchookJames ReevesEmerson Lim Research Open access 02 March 2024 Article: 72
Molecular classification reveals the sensitivity of lung adenocarcinoma to radiotherapy and immunotherapy: multi-omics clustering based on similarity network fusion Jianguo ZhangYangyi LiConghua Xie Research Open access 02 March 2024 Article: 71
Outcomes in biomarker-selected subgroups from the KESTREL study of durvalumab and tremelimumab in recurrent or metastatic head and neck squamous cell carcinoma Tanguy Y. SeiwertSophie WildsmithAmanda Psyrri Research Open access 02 March 2024 Article: 70
Construction of an immune predictive model and identification of TRIP6 as a prognostic marker and therapeutic target of CRC by integration of single-cell and bulk RNA-seq data Wenjun LiuXitu LuoHao Liu Research Open access 02 March 2024 Article: 69
Size selection of intrahepatic lesions for cryoablation contributes to abscopal effect and long-term survival in patients with liver metastatic melanoma receiving PD-1 blockade therapy Lujun ShenHongtong TanWeijun Fan Research Open access 02 March 2024 Article: 68
Neutrophils seeking new neighbors: radiotherapy affects the cellular framework and the spatial organization in a murine breast cancer model C. M. ReichardtM. Muñoz-BecerraL. E. Muñoz Research Open access 02 March 2024 Article: 67
Integrating molecular subtype and CD8+ T cells infiltration to predict treatment response and survival in muscle-invasive bladder cancer Bingyu LiKaifeng JinWeijuan Zhang Research Open access 02 March 2024 Article: 66
Combination of IL-33 with PD-1 blockade augment mILC2s-mediated anti-tumor immunity Jiawei YueHui GuoYumin Wu Research Open access 02 March 2024 Article: 65
Clinical immunotherapy in pancreatic cancer Xiaorong YeYue YuHongdi Ma Review Open access 02 March 2024 Article: 64
Riboflavin-LSD1 axis participates in the in vivo tumor-associated macrophage morphology in human colorectal liver metastases Cristiana SoldaniGiulia De SimoneLaura Brunelli Research Open access 02 March 2024 Article: 63
Mechanism exploration of Zoledronic acid combined with PD-1 in the treatment of hepatocellular carcinoma Xinru FanZijun YanHui Wang Research Open access 02 March 2024 Article: 62
Ectopic CXCR2 expression cells improve the anti-tumor efficiency of CAR-T cells and remodel the immune microenvironment of pancreatic ductal adenocarcinoma Zhengjie DaiXuan LinChen Liu Research Open access 02 March 2024 Article: 61
