1. The application of cytokeratin-18 as a biomarker for drug-induced liver injury

   • Samantha Korver
   • Joanne Bowen
   • Christopher Goldring

   Review Article Open access 29 July 2021 Pages: 3435 - 3448

   

2. Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD⁺-dependent metabolic adaptation

   • Karl Walter Bock

   Review Article Open access 24 September 2021 Pages: 3449 - 3458

   

3. A review of the success and challenges in characterizing human dermal exposure to flame retardants

   • Enzo Zini Moreira Silva
   • Daniel Junqueira Dorta
   • Daniela Morais Leme

   Review Article 26 August 2021 Pages: 3459 - 3473

4. Systems analysis of miRNA biomarkers to inform drug safety

   • Amy L. Schofield
   • Joseph P. Brown
   • Chris Goldring

   Review Article Open access 12 September 2021 Pages: 3475 - 3495

   

5. Cadmium induces renal inflammation by activating the NLRP3 inflammasome through ROS/MAPK/NF-κB pathway in vitro and in vivo

   • Ziyin Li
   • Huiqin Chi
   • Xingfen Yang

   Inorganic Compounds 12 September 2021 Pages: 3497 - 3513

   

6. Toxicokinetics of di-isodecyl phthalate and its major metabolites in rats through the application of a developed and validated UHPLC-ESI-MS/MS method

   • Seung-Hyun Jeong
   • Ji-Hun Jang
   • Yong-Bok Lee

   Toxicokinetics and Metabolism 06 September 2021 Pages: 3515 - 3537

   

7. Cytotoxicity, metabolism, and isozyme mapping of the synthetic cannabinoids JWH-200, A-796260, and 5F-EMB-PINACA studied by means of in vitro systems

   • Tanja M. Gampfer
   • Lea Wagmann
   • Markus R. Meyer

   In vitro systems Open access 28 August 2021 Pages: 3539 - 3557

   

8. Dynamically monitoring cellular γ-H2AX reveals the potential of carcinogenicity evaluation for genotoxic compounds

   • Minmin Qu
   • Hua Xu
   • Jianwei Xie

   Genotoxicity and Carcinogenicity 12 September 2021 Pages: 3559 - 3573

   

9. Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo

   • Zhongwei Liu
   • Neal Shah
   • Weimin Gao

   Genotoxicity and Carcinogenicity 28 August 2021 Pages: 3575 - 3587

   

10. Viper venoms drive the macrophages and hepatocytes to sequester and clear platelets: novel mechanism and therapeutic strategy for venom-induced thrombocytopenia

    • Chuanbin Shen
    • Ming Liu
    • Heyu Ni

    Biologics 14 September 2021 Pages: 3589 - 3599

    

11. Scientific discrepancies in European regulatory proposals on endocrine disruptors—REACH regulation quo vadis?

    • Andreas Natsch

    Letter to the Editor, News and Views Open access 10 September 2021 Pages: 3601 - 3609

12. The codification of hazard and its impact on the hazard versus risk controversy

    • John E. Doe
    • Alan R. Boobis
    • Douglas C. Wolf

    Letter to the Editor, News and Views Open access 24 September 2021 Pages: 3611 - 3621