The evolution of strategies to minimise the risk of human drug-induced liver injury (DILI) in drug discovery and development Paul A. WalkerStephanie RyderRobert J. Riley Review Article Open access 06 May 2020 Pages: 2559 - 2585
Biotransformation of arsenic and toxicological implication of arsenic metabolites Seishiro Hirano Review Article 20 May 2020 Pages: 2587 - 2601
Glutaminases regulate glutathione and oxidative stress in cancer José M. MatésJosé A. Campos-SandovalJavier Márquez Review Article 18 July 2020 Pages: 2603 - 2623
Phospholipids modifications in human hepatoma cell lines (HepG2) exposed to silver and iron oxide nanoparticles Joseph A. AdeyemiCarlos Arterio SorgiFernando Barbosa Jr Nanotoxicology 30 May 2020 Pages: 2625 - 2636
Human variability in isoform-specific UDP-glucuronosyltransferases: markers of acute and chronic exposure, polymorphisms and uncertainty factors E. E. J. KasteelK. DarneyL. S. Lautz Toxicokinetics and Metabolism Open access 15 May 2020 Pages: 2637 - 2661
Xenobiotica-metabolizing enzyme induction potential of chemicals in animal studies: NanoString nCounter gene expression and peptide group-specific immunoaffinity as accelerated and economical substitutions for enzyme activity determinations? Brandy RiffleFranz OeschRobert Landsiedel Toxicokinetics and Metabolism 25 May 2020 Pages: 2663 - 2682
Genetic variants in Ras/Raf/MEK/ERK pathway are associated with gastric cancer risk in Chinese Han population Xiaowei WangXu WuZhengdong Zhang Toxicogenomics and Omics Technologies 11 June 2020 Pages: 2683 - 2690
Proteomic analysis of liver proteins of mice exposed to 1,2-dichloropropane Xiao ZhangKota MorikawaGaku Ichihara Toxicogenomics and Omics Technologies 20 May 2020 Pages: 2691 - 2705
Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals Wanda van der StelGiada CartaPaul Jennings Molecular Toxicology Open access 18 July 2020 Pages: 2707 - 2729
Correction to: Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals Wanda van der StelGiada CartaPaul Jennings Correction 27 July 2020 Pages: 2731 - 2732
An adverse outcome pathway for immune-mediated and allergic hepatitis: a case study with the NSAID diclofenac Saravanakumar SelvarajJung-Hwa OhJürgen Borlak Immunotoxicology Open access 05 May 2020 Pages: 2733 - 2748
Predicting direct hepatocyte toxicity in humans by combining high-throughput imaging of HepaRG cells and machine learning-based phenotypic profiling Faezah HussainSreetama BasuDaniele Zink In vitro systems 12 June 2020 Pages: 2749 - 2767
Potentials and pitfalls of transient in vitro reporter bioassays: interference by vector geometry and cytotoxicity in recombinant zebrafish cell lines Sebastian Lungu-MiteaJohan Lundqvist In vitro systems Open access 23 May 2020 Pages: 2769 - 2784
Hypersensitivity of bladder low threshold, wide dynamic range, afferent fibres following treatment with the chemotherapeutic drugs cyclophosphamide and ifosfamide Kylie A. MillsEleanor J. WestRuss Chess-Williams Organ Toxicity and Mechanisms 22 May 2020 Pages: 2785 - 2797
The cyanobacterial neurotoxin β-N-methylamino-l-alanine (BMAA) targets the olfactory bulb region Paula PierozanElena PirasOskar Karlsson Organ Toxicity and Mechanisms Open access 20 May 2020 Pages: 2799 - 2808
Integrating in vitro data and physiologically based kinetic modeling-facilitated reverse dosimetry to predict human cardiotoxicity of methadone Miaoying ShiHans BouwmeesterMarije Strikwold Organ Toxicity and Mechanisms Open access 04 May 2020 Pages: 2809 - 2827
Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis Christos AndronisJoão Pedro SilvaMiroslav M. Savić Organ Toxicity and Mechanisms Open access 05 June 2020 Pages: 2829 - 2845
Dermal exposure to the UV filter benzophenone-3 during early pregnancy affects fetal growth and sex ratio of the progeny in mice Clarisa Guillermina SantamariaNicole MeyerHoracio Adolfo Rodriguez Reproductive Toxicology 19 May 2020 Pages: 2847 - 2859
Functional genetic variants in centrosome-related genes CEP72 and YWHAG confer susceptibility to gastric cancer Jing NiJinchen WangGuangfu Jin Genotoxicity and Carcinogenicity 13 June 2020 Pages: 2861 - 2872
Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse Zemin WangQiangen WuJames E. Klaunig Genotoxicity and Carcinogenicity 20 May 2020 Pages: 2873 - 2884
Hepatotoxicity of pyrrolizidine alkaloids in rats in relation to human exposure Hermann M. Bolt Letter to the Editor, News and Views Open access 16 July 2020 Pages: 2885 - 2886
Unique human cancer model for acetaldehyde based on Mendelian randomization Mikko SalaspuroDirk W. Lachenmeier Letter to the Editor, News and Views 17 July 2020 Pages: 2887 - 2888
Precision-cut liver slices as an alternative method for long-term hepatotoxicity studies Amnah OthmanSabrina EhnertSeddik Hammad Letter to the Editor, News and Views 18 July 2020 Pages: 2889 - 2891
Heavy metal chelation tests: the misleading and hazardous promise Perrine HoetVincent HaufroidDominique Lison Guest Editorial 16 July 2020 Pages: 2893 - 2896
Correction to: Response to comments on: Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats María M. MilesiVirginia LorenzEnrique H. Luque Correction 24 June 2020 Pages: 2897 - 2898
Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens Miriam N. JacobsAnnamaria ColacciPaule Vasseur Meeting Reports Open access 27 June 2020 Pages: 2899 - 2923