Genome instability in cancer: from mechanisms to the clinic

In this topical collection (6 articles)

1. Method

   De novo identification of expressed cancer somatic mutations from single-cell RNA sequencing data

   Tianyun Zhang, Hanying Jia, Tairan Song, Lin Lv, Doga C. Gulhan… Article:115

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2. Research

   Pre-operative clonal hematopoiesis is related to adverse outcome in lung cancer after adjuvant therapy

   Jae Kwang Yun, Sugyeong Kim, Hongyul An, Geun Dong Lee, Hyeong Ryul Kim… Article:111

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3. Research

   Multi-scale characterisation of homologous recombination deficiency in breast cancer

   Daniel H. Jacobson, Shi Pan, Jasmin Fisher, Maria Secrier Article:90

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4. Research

   Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine

   Anssi Nurminen, Serafiina Jaatinen, Sinja Taavitsainen, Gunilla Högnäs… Article:82

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5. Research

   Full-spectral genome analysis of natural killer/T cell lymphoma highlights impacts of genome instability in driving its progression

   Zegeng Chen, He Huang, Huangming Hong, Huageng Huang, Huawei Weng, Le Yu… Article:48

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6. Research

   Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features

   Srinivasa Rao, Clare Verrill, Lucia Cerundolo, Nasullah Khalid Alham… Article:35

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