Gamete binning: chromosome-level and haplotype-resolved genome assembly enabled by high-throughput single-cell sequencing of gamete genomes
Authors (first, second and last of 12)
Volume 21, issue 1, December 2020
306 articles in this issue
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Potentially adaptive SARS-CoV-2 mutations discovered with novel spatiotemporal and explainable AI models
Authors (first, second and last of 15)
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Convergent network effects along the axis of gene expression during prostate cancer progression
Authors (first, second and last of 30)
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Determinants of Staphylococcus aureus carriage in the developing infant nasal microbiome
Authors (first, second and last of 12)
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GCNG: graph convolutional networks for inferring gene interaction from spatial transcriptomics data
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Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing
Authors (first, second and last of 15)
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STARRPeaker: uniform processing and accurate identification of STARR-seq active regions
Authors (first, second and last of 11)
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Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription
Authors (first, second and last of 12)
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Single-cell transcriptome profiling of an adult human cell atlas of 15 major organs
Authors (first, second and last of 15)
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Metapangenomics of the oral microbiome provides insights into habitat adaptation and cultivar diversity
Authors (first, second and last of 5)
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Functional and genetic markers of niche partitioning among enigmatic members of the human oral microbiome
Authors (first, second and last of 16)
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The Tetracentron genome provides insight into the early evolution of eudicots and the formation of vessel elements
Authors (first, second and last of 36)
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Amplification-free long-read sequencing reveals unforeseen CRISPR-Cas9 off-target activity
Authors (first, second and last of 13)
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Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
Authors (first, second and last of 4)
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Human A-to-I RNA editing SNP loci are enriched in GWAS signals for autoimmune diseases and under balancing selection
Authors (first, second and last of 9)
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Re-assembly of nineteenth-century smallpox vaccine genomes reveals the contemporaneous use of horsepox and horsepox-related viruses in the USA
Authors (first, second and last of 5)
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From FAANG to fork: application of highly annotated genomes to improve farmed animal production
Authors (first, second and last of 14)
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The evolution of relapse of adult T cell acute lymphoblastic leukemia
Authors (first, second and last of 16)
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DNA polymerase epsilon is required for heterochromatin maintenance in Arabidopsis
Authors (first, second and last of 14)
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A pitfall for machine learning methods aiming to predict across cell types
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Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus
Authors (first, second and last of 28)
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A versatile toolkit for CRISPR-Cas13-based RNA manipulation in Drosophila
Authors (first, second and last of 4)
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Navigating the crowd: visualizing coordination between genome dynamics, structure, and transcription
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A DNA methylation state transition model reveals the programmed epigenetic heterogeneity in human pre-implantation embryos
Authors (first, second and last of 7)
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Do malignant cells sleep at night?
Authors (first, second and last of 7)
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Massive gene presence-absence variation shapes an open pan-genome in the Mediterranean mussel
Authors (first, second and last of 21)
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SVFX: a machine learning framework to quantify the pathogenicity of structural variants
Authors (first, second and last of 4)
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Pathway information extracted from 25 years of pathway figures
Authors (first, second and last of 4)
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Fission yeast condensin contributes to interphase chromatin organization and prevents transcription-coupled DNA damage
Authors (first, second and last of 8)
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Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity
Authors (first, second and last of 46)
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Publisher Correction: Bayesian model selection reveals biological origins of zero inflation in single-cell transcriptomics
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Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression
Authors (first, second and last of 12)
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RNA editing in cancer impacts mRNA abundance in immune response pathways
Authors (first, second and last of 8)
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Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions
Authors (first, second and last of 22)
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High throughput single-cell detection of multiplex CRISPR-edited gene modifications
Authors (first, second and last of 16)
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The design and construction of reference pangenome graphs with minigraph
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Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
Authors (first, second and last of 26)
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Multiplex enCas12a screens detect functional buffering among paralogs otherwise masked in monogenic Cas9 knockout screens
Authors (first, second and last of 4)
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iMOKA: k-mer based software to analyze large collections of sequencing data
Authors (first, second and last of 6)
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AlphaBeta: computational inference of epimutation rates and spectra from high-throughput DNA methylation data in plants
Authors (first, second and last of 12)
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A genome assembly and the somatic genetic and epigenetic mutation rate in a wild long-lived perennial Populus trichocarpa
Authors (first, second and last of 25)
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An integrated peach genome structural variation map uncovers genes associated with fruit traits
Authors (first, second and last of 15)
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Prime editing efficiently generates W542L and S621I double mutations in two ALS genes in maize
Authors (first, second and last of 11)
