Synthetic biology

In this topical collection (57 articles)

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1. Research article

   The evolution of metabolic networks of E. coli

   David J Baumler, Roman G Peplinski, Jennifer L Reed… Article:182

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2. Research article

   DENSE: efficient and prior knowledge-driven discovery of phenotype-associated protein functional modules

   Willam Hendrix, Andrea M Rocha, Kanchana Padmanabhan, Alok Choudhary… Article:172

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3. Research article

   Multi-objective optimization of enzyme manipulations in metabolic networks considering resilience effects

   Wu-Hsiung Wu, Feng-Sheng Wang, Maw-Shang Chang Article:145

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4. Research article

   Rapid construction of metabolic models for a family of Cyanobacteria using a multiple source annotation workflow

   Thomas J Mueller, Bertram M Berla, Himadri B Pakrasi… Article:142

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5. Methodology article

   Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models

   Carlos Pozo, Alberto Marín-Sanguino, Rui Alves… Article:137

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6. Methodology article

   Computational codon optimization of synthetic gene for protein expression

   Bevan Kai-Sheng Chung, Dong-Yup Lee Article:134

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7. Research article

   Hierarchy of non-glucose sugars in Escherichia coli

   Guy Aidelberg, Benjamin D Towbin, Daphna Rothschild, Erez Dekel… Article:133

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8. Research article

   Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach

   Rutger D Douma, Joana M Batista, Kai M Touw, Jan AKW Kiel… Article:132

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9. Methodology article

   (Im)Perfect robustness and adaptation of metabolic networks subject to metabolic and gene-expression regulation: marrying control engineering with metabolic control analysis

   Fei He, Vincent Fromion, Hans V Westerhoff Article:131

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10. Research article

    Gene autoregulation via intronic microRNAs and its functions

    Carla Bosia, Matteo Osella, Mariama El Baroudi, Davide Corà… Article:131

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11. Research article

    Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation

    Tao You, Ian Stansfield, M Carmen Romano, Alistair JP Brown… Article:131

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12. Research article

    Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052

    Caroline B Milne, James A Eddy, Ravali Raju, Soroush Ardekani… Article:130

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13. Research Article

    A computational method for the investigation of multistable systems and its application to genetic switches

    Miriam Leon, Mae L. Woods, Alex J. H. Fedorec, Chris P. Barnes Article:130

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14. Research article

    Photo-sensitive degron variants for tuning protein stability by light

    Svetlana Usherenko, Hilke Stibbe, Massimiliano Muscó… Article:128

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15. Research article

    Comparative multi-goal tradeoffs in systems engineering of microbial metabolism

    David Byrne, Alexandra Dumitriu, Daniel Segrè Article:127

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16. Research article

    A reconfigurable NAND/NOR genetic logic gate

    Angel Goñi-Moreno, Martyn Amos Article:126

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17. Methodology Article

    GoldenPiCS: a Golden Gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris

    Roland Prielhofer, Juan J. Barrero, Stefanie Steuer, Thomas Gassler… Article:123

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18. Methodology article

    A retrosynthetic biology approach to metabolic pathway design for therapeutic production

    Pablo Carbonell, Anne-Gaëlle Planson, Davide Fichera… Article:122

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19. Methodology Article

    Designing synthetic networks in silico: a generalised evolutionary algorithm approach

    Robert W. Smith, Bob van Sluijs, Christian Fleck Article:118

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20. Methodology Article

    Multicriteria global optimization for biocircuit design

    Irene Otero-Muras, Julio R Banga Article:113

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