1. Does ‘Strong Analgesic’ Equal ‘Strong Opioid’? Tapentadol and the Concept of ‘µ-Load’

   • Robert B. Raffa
   • Christian Elling
   • Thomas M. Tzschentke

   Commentary Open access 11 September 2018 Pages: 1471 - 1484

   

2. A Charter to Improve Patient Care in Severe Asthma

   • Andrew Menzies-Gow
   • G-Walter Canonica
   • Antje-Henriette Fink-Wagner

   Commentary Open access 04 September 2018 Pages: 1485 - 1496

   

3. An Update of Efficacy and Safety of Cetuximab in Metastatic Colorectal Cancer: A Narrative Review

   • Giulia Fornasier
   • Sara Francescon
   • Paolo Baldo

   Review 14 September 2018 Pages: 1497 - 1509

   

4. Current and Emerging Treatment Modalities for Leber’s Hereditary Optic Neuropathy: A Review of the Literature

   • Anna Theodorou-Kanakari
   • Spyridon Karampitianis
   • Irini Chatziralli

   Review Open access 01 September 2018 Pages: 1510 - 1518

5. Diagnosis and Management of Hypothyroidism: Addressing the Knowledge–Action Gaps

   • Sanjay Kalra
   • A. K. Das
   • Nitin Mulgaonkar

   Review 31 August 2018 Pages: 1519 - 1534

   

6. Efficacy of Monotherapy with Biologics and JAK Inhibitors for the Treatment of Rheumatoid Arthritis: A Systematic Review

   • Paul Emery
   • Janet E. Pope
   • Blerina Kola

   Review Open access 20 August 2018 Pages: 1535 - 1563

   

7. Comparative Effectiveness of nab-Paclitaxel Plus Gemcitabine vs FOLFIRINOX in Metastatic Pancreatic Cancer: A Retrospective Nationwide Chart Review in the United States

   • Sunnie Kim
   • James E. Signorovitch
   • John L. Marshall

   Original Research Open access 12 September 2018 Pages: 1564 - 1577

   

8. Diagnostic Accuracy of Bronchodilator Response for Asthma in a Population of South China

   • Shichuan Zhang
   • Chengping Hu
   • Juntao Feng

   Original Research 12 September 2018 Pages: 1578 - 1584

   

9. Predicting Responses to Pregabalin for Painful Diabetic Peripheral Neuropathy Based on Trajectory-Focused Patient Profiles Derived from the First 4 Weeks of Treatment

   • Roger A. Edwards
   • Gianluca Bonfanti
   • Joe Alexander

   Original Research Open access 11 September 2018 Pages: 1585 - 1597

   

10. 72-Week Safety and Tolerability of Dimethyl Fumarate in Japanese Patients with Relapsing-remitting Multiple Sclerosis: Analysis of the Randomised, Double Blind, Placebo-Controlled, Phase III APEX Study and its Open-Label Extension

    • Hirofumi Ochi
    • Masaaki Niino
    • Shinichi Torii

    Original Research Open access 11 September 2018 Pages: 1598 - 1611

    

11. Medication Adherence and Discontinuation of Aripiprazole Once-Monthly 400 mg (AOM 400) Versus Oral Antipsychotics in Patients with Schizophrenia or Bipolar I Disorder: A Real-World Study Using US Claims Data

    • Tingjian Yan
    • Mallik Greene
    • Michael S. Broder

    Original Research Open access 11 September 2018 Pages: 1612 - 1625

    

12. Preventing Clinically Important Deterioration of COPD with Addition of Umeclidinium to Inhaled Corticosteroid/Long-Acting β₂-Agonist Therapy: An Integrated Post Hoc Analysis

    • Ian P. Naya
    • Lee Tombs
    • Chris Compton

    Original Research Open access 06 September 2018 Pages: 1626 - 1638

    

13. Treatment Duration, Healthcare Resource Utilization, and Costs Among Chemotherapy-Naïve Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Enzalutamide or Abiraterone Acetate: A Retrospective Claims Analysis

    • Neil M. Schultz
    • Scott C. Flanders
    • Vahan Kassabian

    Original Research Open access 06 September 2018 Pages: 1639 - 1655

    

14. Neuroplasticity, Neurotransmission and Brain-Related Genes in Major Depression and Bipolar Disorder: Focus on Treatment Outcomes in an Asiatic Sample

    • Marco Calabrò
    • Laura Mandelli
    • Alessandro Serretti

    Original Research Open access 03 September 2018 Pages: 1656 - 1670

15. Burden of Infections Among Chronic Myeloid Leukemia Patients Receiving Dasatinib or Nilotinib: A Real-World Retrospective Healthcare Claims Study in the United States

    • Karen Seiter
    • Dominick Latremouille-Viau
    • George J. Joseph

    Original Research 28 August 2018 Pages: 1671 - 1685

    

16. Expected Budget Impact and Health Outcomes of Expanded Use of Vagus Nerve Stimulation Therapy for Drug-Resistant Epilepsy

    • Molly F. Purser
    • Deirdre M. Mladsi
    • John Forsey

    Original Research Open access 24 August 2018 Pages: 1686 - 1696

    

17. Correction to: Expected Budget Impact and Health Outcomes of Expanded Use of Vagus Nerve Stimulation Therapy for Drug-Resistant Epilepsy

    • Molly F. Purser
    • Deirdre M. Mladsi
    • John Forsey

    Correction Open access 12 September 2018 Pages: 1697 - 1697

18. Combination Antihypertensive Therapy with Perindopril and Indapamide in Patients with Essential Hypertension: Effect on Endothelial and Cognitive Markers of Vascular Improvement

    • Elena A. Zheleznykh
    • Yulia A. Danilogorskaya
    • Mikhail I. Tishman

    Original Research 20 August 2018 Pages: 1698 - 1712

    

19. Real-world Management of Women with Postmenopausal Osteoporosis Treated with Denosumab: A Prospective Observational Study in the Czech Republic and Slovakia

    • Olga Růžičková
    • Zdenko Killinger
    • Lama Kalouche-Khalil

    Brief Report Open access 06 September 2018 Pages: 1713 - 1728