Progressively Reducing Regulatory Burden Vinod P. ShahTodd L. CecilRoger L. Williams Commentary 17 April 2014 Pages: 621 - 624
When Assay Format Matters: a Case Study on the Evaluation of Three Assay Formats to Support a Clinical Pharmacokinetic Study Kun PengDana BakerSaloumeh K. Fischer Research Article 22 April 2014 Pages: 625 - 633
Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics Bhagwat PrasadJashvant D. Unadkat Review Article 22 April 2014 Pages: 634 - 648
Curcumin Inhibits the AKT/NF-κB Signaling via CpG Demethylation of the Promoter and Restoration of NEP in the N2a Cell Line Yushuang DengXi LuGang Yu Research Article 23 April 2014 Pages: 649 - 657
Assessment and Reporting of the Clinical Immunogenicity of Therapeutic Proteins and Peptides—Harmonized Terminology and Tactical Recommendations G. ShankarS. ArkinS. Yim White Paper 24 April 2014 Pages: 658 - 673
Anti-HIV Drug Development Through Computational Methods Wan-Gang GuXuan ZhangJun-Fa Yuan Review Article 24 April 2014 Pages: 674 - 680
Impact-Insertion Applicator Improves Reliability of Skin Penetration by Solid Microneedle Arrays Koen van der MaadenEmine SekerdagJoke Bouwstra Brief/Technical Note 24 April 2014 Pages: 681 - 684
In Vitro Characterization of a Novel Polymeric System for Preparation of Amorphous Solid Drug Dispersions Zahra N. MahmoudiSampada B. UpadhyeAli R. Rajabi-Siahboomi Research Article 02 May 2014 Pages: 685 - 697
Nanomedicine Drug Development: A Scientific Symposium Entitled “Charting a Roadmap to Commercialization” Gregory FinchHenry HavelMan Liu Meeting Report 13 May 2014 Pages: 698 - 704
Pharmacokinetics and Pharmacodynamics of Phenethyl Isothiocyanate: Implications in Breast Cancer Prevention Marilyn E. MorrisRutwij A. Dave Review Article 13 May 2014 Pages: 705 - 713
Quantitative Targeted Proteomics for Membrane Transporter Proteins: Method and Application Xi QiuHui ZhangYurong Lai Review Article 15 May 2014 Pages: 714 - 726
Apigenin Reactivates Nrf2 Anti-oxidative Stress Signaling in Mouse Skin Epidermal JB6 P + Cells Through Epigenetics Modifications Ximena Paredes-GonzalezFrancisco FuentesAh-Ng Tony Kong Research Article 16 May 2014 Pages: 727 - 735
Mechanism-Based Pharmacokinetic Modeling to Evaluate Transporter-Enzyme Interplay in Drug Interactions and Pharmacogenetics of Glyburide Manthena V. S. VarmaRenato J. ScialisXin Yang Research Article 17 May 2014 Pages: 736 - 748
Practical Considerations for Dose Selection in Pediatric Patients to Ensure Target Exposure Requirements April M. BarbourMichael J. FosslerJeffrey Barrett Commentary 20 May 2014 Pages: 749 - 755
Mechanistic Modeling of Monocarboxylate Transporter-Mediated Toxicokinetic/Toxicodynamic Interactions Between γ-Hydroxybutyrate and l-Lactate Bridget L. MorseNisha VijayMarilyn E. Morris Research Article 23 May 2014 Pages: 756 - 770
Understanding Pharmaceutical Quality by Design Lawrence X. YuGregory AmidonJanet Woodcock Review Article 23 May 2014 Pages: 771 - 783
Measurement of Subvisible Particulates in Lyophilised Erwinia chrysanthemi l-asparaginase and Relationship with Clinical Experience David GervaisTim CornAlan Jennings Research Article Open access 23 May 2014 Pages: 784 - 790
Statistical Comparison of Dissolution Profiles to Predict the Bioequivalence of Extended Release Formulations J. D. Gomez-MantillaU. F. SchaeferC. M. Lehr Research Article 23 May 2014 Pages: 791 - 801
Permeability Comparison between Hepatocyte and Low Efflux MDCKII Cell Monolayer Rui LiYi-An BiLi Di Research Article 23 May 2014 Pages: 802 - 809
Simplification of Complex Physiologically Based Pharmacokinetic Models of Monoclonal Antibodies Mohamed ElmeliegyPhilip LoweWojciech Krzyzanski Research Article 29 May 2014 Pages: 810 - 842
A Sequential Bioequivalence Design with a Potential Ethical Advantage Anders Fuglsang Research Article 29 May 2014 Pages: 843 - 846
Many Approved Drugs Have Bioactive Analogs With Different Target Annotations Ye HuEugen LounkineJürgen Bajorath Research Article 29 May 2014 Pages: 847 - 859
Release Behaviour of Single Pellets and Internal Fine 3D Structural Features Co-define the In Vitro Drug Release Profile Shuo YangXianzhen YinJiwen Zhang Research Article 30 May 2014 Pages: 860 - 871
The Gender of Cell Lines Matters When Screening for Novel Anti-Cancer Drugs Larissa M. NunesElisa Robles-EscajedaArmando Varela-Ramirez Brief/Technical Note 30 May 2014 Pages: 872 - 874
Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs III — the Effect of Fed State Conditions on the In Vitro Release and Degradation of Desmopressin Philip C. ChristophersenDimple VaghelaHuiling Mu Research Article 30 May 2014 Pages: 875 - 883