A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs Silvan R. UrferTammi L. KaeberleinMatt Kaeberlein Original Article 03 April 2017 Pages: 117 - 127
IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan Nicole M. AshpoleSreemathi LoganWilliam E. Sonntag Original Article 13 April 2017 Pages: 129 - 145
The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer Andrej PodlutskyMarta Noa Valcarcel-AresZoltan Ungvari Original Article 23 February 2017 Pages: 147 - 160
Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells Kevin M. PerrottChristopher D. WileyJudith Campisi Original Article 04 April 2017 Pages: 161 - 173
Influence of Nrf2 activators on subcellular skeletal muscle protein and DNA synthesis rates after 6 weeks of milk protein feeding in older adults Adam R. KonopkaJaime L. LaurinBenjamin F. Miller Original Article 10 March 2017 Pages: 175 - 186
A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse Sathyaseelan S. DeepaShylesh BhaskaranArlan Richardson Original Article Open access 13 April 2017 Pages: 187 - 198
Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey Eli ShobinMichael P. BowleyDouglas L. Rosene Original Article 25 February 2017 Pages: 199 - 220
The association between frailty, the metabolic syndrome, and mortality over the lifespan Alice E. KaneEdward GregsonSusan E. Howlett Original Article 09 March 2017 Pages: 221 - 229
Cognitive status, fast walking speed and walking speed reserve—the Gait and Alzheimer Interactions Tracking (GAIT) study Michele L. CallisayaCyrille P. LaunayOlivier Beauchet Original Article 03 April 2017 Pages: 231 - 239
Norman S. Wolf, D.V.M., Ph.D., 1927–2017: experimental pathologist and geroscientist George M. Martin Obituary 05 April 2017 Pages: 241 - 244