Predicting Human Oral Bioavailability of a Compound: Development of a Novel Quantitative Structure-Bioavailability Relationship C. Webster AndrewsLee BennettLawrence X. Yu OriginalPaper Pages: 639 - 644
New Insights into the Pharmacokinetics and Metabolism of (R,S)-Ifosfamide in Cancer Patients Using a Population Pharmacokinetic-Metabolism Model Marika Pasternyk Di MarcoIrving W. WainerMurray P. Ducharme OriginalPaper Pages: 645 - 652
Pharmacokinetic-Pharmacodynamic Analysis of the EEG Effect of Alfentanil in Rats Followingβ-Funaltrexamine-Induced μOpioid Receptor “Knockdown”In Vivo >Maria GarridoJosy Gubbens-StibbePiet H. van der Graaf OriginalPaper Pages: 653 - 659
Prediction of In Vivo Tissue Distribution from In Vitro Data 1. Experiments with Markers of Aqueous Spaces Peter BallardDavid E. LeahyMalcolm Rowland OriginalPaper Pages: 660 - 663
Permeability and Diffusion in Vitreous Humor: Implications for Drug Delivery Jing XuJeffrey J. HeysTheodore W. Randolph OriginalPaper Pages: 664 - 669
Controlled Release of Liposomes from Biodegradable Dextran Microspheres: A Novel Delivery Concept Robert J. H. StenekesArjen E. LoebisWim E. Hennink OriginalPaper Pages: 664 - 669
Air-Interface Condition Promotes the Formation of Tight Corneal Epithelial Cell Layers for Drug Transport Studies Joan-En ChangSujit K. BasuVincent H. L. Lee OriginalPaper Pages: 670 - 676
Stabilization of Vinca Alkaloids Encapsulated in Poly(lactide-co-glycolide) Microspheres Julia MarininaAnna ShenderovaSteven P. Schwendeman OriginalPaper Pages: 677 - 683
Preparation of Biodegradable Insulin Nanocapsules from Biocompatible Microemulsions Suchat WatnasirichaikulNigel M. DaviesIan G. Tucker OriginalPaper Pages: 684 - 689
An Evaluation of the Use of Modulated Temperature DSC as a Means of Assessing the Relaxation Behaviour of Amorphous Lactose Duncan Q. M. CraigMerete BarsnesVicky L. Kett OriginalPaper Pages: 696 - 700
Simultaneous Determination of the Heat and the Quantity of Vapor Sorption Using a Novel Microcalorimetric Method Vesa-Pekka LehtoEnsio Lain OriginalPaper Pages: 701 - 706
Polyisobutylcyanoacrylate Nanocapsules Containing an Aqueous Core as a Novel Colloidal Carrier for the Delivery of Oligonucleotides Gregory LambertElias FattalPatrick Couvreur OriginalPaper Pages: 707 - 714
Synthesis and Cytotoxic Evaluation of a Series of γ-Substituted γ-Aryloxymethyl-α-methylene-γ-butyrolactones Against Cancer Cells Cheng-Chyi TzengKuan-Han LeeYeh-Long Chen OriginalPaper Pages: 715 - 719
Induction of T Cell Anergy by Liposomes with Incorporated Major Histocompatibility Complex (MHC) II/Peptide Complexes Annemiek J. M. L. van RensenLeonie S. TaamsMarca H. M. Wauben OriginalPaper Pages: 720 - 726
2D and 3D QSAR Analysis of Some Valproic Acid Metabolites and Analogues as Anticonvulsant Agents Tatiana NetzevaIrini DoytchinovaRoumiana Natcheva OriginalPaper Pages: 727 - 732
The Effect of Nasal Patency on the Clearance of Radiolabeled Saline in Healthy Volunteers Neena WashingtonJulian A. McGlashanDavid A. Gill OriginalPaper Pages: 733 - 736
Transfer of Dopamine in the Olfactory Pathway Following Nasal Administration in Mice Maria DahlinUlrika BergmanEva Brittebo OriginalPaper Pages: 737 - 742
Biovector™ Nanoparticles Improve Antinociceptive Efficacy of Nasal Morphine Didier BetbederSandrine SpérandioBernard Francés OriginalPaper Pages: 743 - 748
Morphine Antinociception Is Enhanced in mdr1a Gene-Deficient Mice Jian ZongGary M. Pollack OriginalPaper Pages: 749 - 753
Permeation Studies In Vitro and In Vivo of Potential Radiopharmaceuticals with Affinity to Neuro Receptors Matthias FriebeKayoshi SudaHeidi Wunderli-Allenspach OriginalPaper Pages: 754 - 760
Carrier-Mediated Transport of Macrolide Antimicrobial Agents Across Caco-2 Cell Monolayers Hidetaka SaitoYoshiki FukasawaShinji Yamashita OriginalPaper Pages: 761 - 765