PBPK model for antibody disposition in mouse brain: validation using large-pore microdialysis data Shengjia WuFlorie Le PrieultDhaval K. Shah Original Paper 10 September 2022 Pages: 579 - 592
A quantitative systems pharmacology model for simulating OFF-Time in augmentation trials for Parkinson’s disease: application to preladenant Rachel RoseEmma MitchellHugo Geerts Original Paper 09 October 2022 Pages: 593 - 606
Physiologically-based pharmacokinetic model for pulmonary disposition of protein therapeutics in humans Prabhas JagdaleArmin SeppDhaval K. Shah Original Paper 20 October 2022 Pages: 607 - 624
Accelerating robust plausible virtual patient cohort generation by substituting ODE simulations with parameter space mapping Thibaud DerippeSylvain FouliardDonald E. Mager Original Paper 31 October 2022 Pages: 625 - 644
A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis Feiyan LiuLinda B. S. AulinJohan G. C. van Hasselt Original Paper Open access 19 October 2022 Pages: 645 - 655
Modeling of the effect of cerebrospinal fluid flow modulation on locally delivered drugs in the brain Caroline M. WoodVeronica E. FaragJay C. Sy Original Paper 25 October 2022 Pages: 657 - 671