Concentration-QTc analysis with two or more correlated baselines Yasushi OrihashiYuji Kumagai Original Paper 12 May 2021 Pages: 615 - 622
Pharmacometric estimation methods for aggregate data, including data simulated from other pharmacometric models Pyry Antti Juhana Välitalo Original Paper Open access 22 June 2021 Pages: 623 - 638
A physiologically-based pharmacokinetic model to describe antisense oligonucleotide distribution after intrathecal administration Michael MonineDaniel NorrisIvan Nestorov Original Paper 15 May 2021 Pages: 639 - 654
A comparison of covariate selection techniques applied to pre-exposure prophylaxis (PrEP) drug concentration data in men and transgender women at risk for HIV Skyler PetersonMustafa IbrahimSamantha MaWhinney Original Paper 19 May 2021 Pages: 655 - 669
A latent variable approach to account for correlated inputs in global sensitivity analysis Nicola MelilloAdam S. Darwich Original Paper Open access 25 May 2021 Pages: 671 - 686
A quantitative systems pharmacology model of hyporesponsiveness to erythropoietin in rats Ly Minh NguyenZhichuan LiWojciech Krzyzanski Original Paper 07 June 2021 Pages: 687 - 710
Modeling of levothyroxine in newborns and infants with congenital hypothyroidism: challenges and opportunities of a rare disease multi-center study Gilbert KochBritta SteffensMarc Pfister Original Paper Open access 11 June 2021 Pages: 711 - 723
Lumbar cerebrospinal fluid-to-brain extracellular fluid surrogacy is context-specific: insights from LeiCNS-PK3.0 simulations Mohammed A. A. SalehChi Fong LooElizabeth C. M. De Lange Original Paper Open access 17 June 2021 Pages: 725 - 741
Two-pore physiologically based pharmacokinetic model validation using whole-body biodistribution of trastuzumab and different-size fragments in mice Zhe LiYingyi LiDhaval K. Shah Original Paper 19 June 2021 Pages: 743 - 762
