1. An automated sampling importance resampling procedure for estimating parameter uncertainty

   • Anne-Gaëlle Dosne
   • Martin Bergstrand
   • Mats O. Karlsson

   Original Paper Open access 08 September 2017 Pages: 509 - 520

   

2. Quantitative modeling of the dynamics and intracellular trafficking of far-red light-activatable prodrugs: implications in stimuli-responsive drug delivery system

   • Mengjie Li
   • Pritam Thapa
   • Sukyung Woo

   Original Paper 14 September 2017 Pages: 521 - 536

   

3. Platform model describing pharmacokinetic properties of vc-MMAE antibody–drug conjugates

   • Matts Kågedal
   • Leonid Gibiansky
   • Chunze Li

   Original Paper 16 September 2017 Pages: 537 - 548

   

4. Evaluation and calibration of high-throughput predictions of chemical distribution to tissues

   • Robert G. Pearce
   • R. Woodrow Setzer
   • John F. Wambaugh

   Original Paper 14 October 2017 Pages: 549 - 565

   

5. Population pharmacokinetics of gabapentin in healthy Korean subjects with influence of genetic polymorphisms of ABCB1

   • Phuong Tran
   • Hee-Doo Yoo
   • Yong-Bok Lee

   Original Paper 10 October 2017 Pages: 567 - 579

   

6. Model selection and averaging of nonlinear mixed-effect models for robust phase III dose selection

   • Yasunori Aoki
   • Daniel Röshammar
   • Andrew C. Hooker

   Original Paper Open access 04 November 2017 Pages: 581 - 597

   

7. A model of fracture risk used to examine the link between bone mineral density and the impact of different therapeutic mechanisms on fracture outcomes in patients with osteoporosis

   • Rena J. Eudy-Byrne
   • William Gillespie
   • Marc R. Gastonguay

   Original Paper 28 October 2017 Pages: 599 - 609

   

8. Assessing robustness of designs for random effects parameters for nonlinear mixed-effects models

   • Stephen B. Duffull
   • Andrew C. Hooker

   Original Paper 24 October 2017 Pages: 611 - 616

   

9. PKPD modeling of acquired resistance to anti-cancer drug treatment

   • Miro J. Eigenmann
   • Nicolas Frances
   • Antje-Christine Walz

   Original Paper Open access 31 October 2017 Pages: 617 - 630

   

10. Comparison of tenofovir plasma and tissue exposure using a population pharmacokinetic model and bootstrap: a simulation study from observed data

    • Jon W. Collins
    • J. Heyward Hull
    • Julie B. Dumond

    Original Paper 08 November 2017 Pages: 631 - 640